ARP6_ASHGO
ID ARP6_ASHGO Reviewed; 410 AA.
AC Q74ZV8;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Actin-like protein ARP6;
GN Name=ARP6; OrderedLocusNames=AGR091W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC transcriptional regulation of selected genes by chromatin remodeling.
CC Involved in chromosome stability (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the SWR1 chromatin remodeling complex.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton
CC {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the actin family. ARP6 subfamily. {ECO:0000305}.
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DR EMBL; AE016820; AAS54580.1; -; Genomic_DNA.
DR RefSeq; NP_986756.1; NM_211818.1.
DR AlphaFoldDB; Q74ZV8; -.
DR SMR; Q74ZV8; -.
DR STRING; 33169.AAS54580; -.
DR EnsemblFungi; AAS54580; AAS54580; AGOS_AGR091W.
DR GeneID; 4623058; -.
DR KEGG; ago:AGOS_AGR091W; -.
DR eggNOG; KOG0680; Eukaryota.
DR HOGENOM; CLU_027965_1_1_1; -.
DR InParanoid; Q74ZV8; -.
DR OMA; FFEEYEC; -.
DR Proteomes; UP000000591; Chromosome VII.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR GO; GO:0000812; C:Swr1 complex; IBA:GO_Central.
DR GO; GO:0031491; F:nucleosome binding; IBA:GO_Central.
DR GO; GO:0043486; P:histone exchange; IBA:GO_Central.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR030054; Arp6.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR PANTHER; PTHR11937:SF47; PTHR11937:SF47; 1.
DR Pfam; PF00022; Actin; 1.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
PE 3: Inferred from homology;
KW Activator; Chromatin regulator; Cytoplasm; Cytoskeleton; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..410
FT /note="Actin-like protein ARP6"
FT /id="PRO_0000089110"
SQ SEQUENCE 410 AA; 47637 MW; 25E7480CC6378FBB CRC64;
MRVPLLMENG SYEIKFGPAN LETPYRARNC LTRDRYGRYH LSNQMDQIRD ISHCHIRRPS
ELGQLISWEL EEQIWDYCLF NPDEFGWELK DSKDVDLIAS ETCMTIPEIS KNMDQVVFEE
YEFGSMMKCP VAQFVPFDRA RDYDIVGGAG EVVEAKSGYN NFQLVVDSGF NCTWVMPVIK
GVPYYKATKK LDIGGRFLNG LLKETISFRH YNVMDETILI NNIKEQCCFM PPVSYFDSFQ
RKEETRVEYI LPDFQTSLIG YVRQPKQAIP KTSQILRLED ELFTVPETFF HPEISNILKP
GLVETILECV SMVPEVLRPL LVSNIVAVGG NFNIANFATR LATELQRQCP TDWKVRVHQP
KLDAALQGWK SMRQFSQTDS YKNSRVTRSE YLEHGADWCT KHRFGYEQWI
