ARP6_CAEEL
ID ARP6_CAEEL Reviewed; 418 AA.
AC Q09443; Q17351;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 25-MAR-2003, sequence version 3.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Actin-like protein C08B11.6;
GN Name=arp-6; ORFNames=C08B11.6;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RC STRAIN=Bristol N2;
RX PubMed=9163526; DOI=10.1093/oxfordjournals.jbchem.a021648;
RA Tanaka Y., Ohta A., Terashima K., Sakamoto H.;
RT "Polycistronic expression and RNA-binding specificity of the C. elegans
RT homologue of the spliceosome-associated protein SAP49.";
RL J. Biochem. 121:739-745(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC -!- DEVELOPMENTAL STAGE: Expressed throughout development.
CC {ECO:0000269|PubMed:9163526}.
CC -!- SIMILARITY: Belongs to the actin family. ARP6 subfamily. {ECO:0000305}.
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DR EMBL; U24189; AAC47513.1; -; mRNA.
DR EMBL; Z46676; CAA86667.3; -; Genomic_DNA.
DR PIR; T19072; T19072.
DR RefSeq; NP_495681.4; NM_063280.5.
DR AlphaFoldDB; Q09443; -.
DR SMR; Q09443; -.
DR BioGRID; 39620; 2.
DR STRING; 6239.C08B11.6; -.
DR EPD; Q09443; -.
DR PaxDb; Q09443; -.
DR PeptideAtlas; Q09443; -.
DR EnsemblMetazoa; C08B11.6.1; C08B11.6.1; WBGene00007434.
DR GeneID; 174288; -.
DR KEGG; cel:CELE_C08B11.6; -.
DR UCSC; C08B11.6.1; c. elegans.
DR CTD; 174288; -.
DR WormBase; C08B11.6; CE30856; WBGene00007434; arp-6.
DR eggNOG; KOG0680; Eukaryota.
DR GeneTree; ENSGT00720000108833; -.
DR HOGENOM; CLU_027965_1_1_1; -.
DR InParanoid; Q09443; -.
DR OMA; MEPNKET; -.
DR OrthoDB; 649708at2759; -.
DR PhylomeDB; Q09443; -.
DR PRO; PR:Q09443; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00007434; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0000812; C:Swr1 complex; IBA:GO_Central.
DR GO; GO:0031491; F:nucleosome binding; IBA:GO_Central.
DR GO; GO:0043486; P:histone exchange; IBA:GO_Central.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR030054; Arp6.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR PANTHER; PTHR11937:SF47; PTHR11937:SF47; 1.
DR Pfam; PF00022; Actin; 1.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
PE 2: Evidence at transcript level;
KW Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..418
FT /note="Actin-like protein C08B11.6"
FT /id="PRO_0000089109"
FT CONFLICT 229
FT /note="E -> G (in Ref. 1; AAC47513)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 418 AA; 47618 MW; EB8F09E6B103E9C8 CRC64;
MSLTTIIFDN GGHNMKIGTI DSESPRLVPN SIVKAKHEKK RVFVAHEQEE CSDKFSLFYV
RPIERGYVVN WDTQQQIWEK TFGSMDVEAS TSRIALTDNN YLIPALPDVS SEILFDYFGF
TEVHKTSAST LVAKHSNKIN NEKCAVVVDS GFSWTTVASF VNGMLIQDSV IRIDVGGKAL
TNKLKDWVSY RQLNVSEETY VINECKEDLC FVSQNFDESM KEARNRFQEN TTMKRYIMPD
FHSTFRGVVK DVKEPHDPQI PSIHLGVERF AIPEILFNPS DIDIDQCGVA EAVIESICQC
PEALRPALAE NIIVIGGSSC FPGFRERLER EVRSMLPAEY GLNVSNDVIN PQTHSWHCGQ
ELLTASKVPW INRKDWDERG DSLEFSNFFQ TLVQSDELKG TRNFDDQREK SPKEDEDF