ID   ARP6_CANGA              Reviewed;         421 AA.
AC   Q6FKE7;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Actin-like protein ARP6;
GN   Name=ARP6; OrderedLocusNames=CAGL0L12166g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC       dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC       transcriptional regulation of selected genes by chromatin remodeling.
CC       Involved in chromosome stability (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the SWR1 chromatin remodeling complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton
CC       {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the actin family. ARP6 subfamily. {ECO:0000305}.
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DR   EMBL; CR380958; CAG62271.1; -; Genomic_DNA.
DR   RefSeq; XP_449297.1; XM_449297.1.
DR   AlphaFoldDB; Q6FKE7; -.
DR   SMR; Q6FKE7; -.
DR   STRING; 5478.XP_449297.1; -.
DR   EnsemblFungi; CAG62271; CAG62271; CAGL0L12166g.
DR   GeneID; 2890687; -.
DR   KEGG; cgr:CAGL0L12166g; -.
DR   CGD; CAL0135506; CAGL0L12166g.
DR   VEuPathDB; FungiDB:CAGL0L12166g; -.
DR   eggNOG; KOG0680; Eukaryota.
DR   HOGENOM; CLU_027965_1_1_1; -.
DR   InParanoid; Q6FKE7; -.
DR   OMA; FFEEYEC; -.
DR   Proteomes; UP000002428; Chromosome L.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR   GO; GO:0000812; C:Swr1 complex; IEA:EnsemblFungi.
DR   GO; GO:0031491; F:nucleosome binding; IEA:EnsemblFungi.
DR   GO; GO:0043486; P:histone exchange; IEA:EnsemblFungi.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR030054; Arp6.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   PANTHER; PTHR11937:SF47; PTHR11937:SF47; 1.
DR   Pfam; PF00022; Actin; 1.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
PE   3: Inferred from homology;
KW   Activator; Chromatin regulator; Cytoplasm; Cytoskeleton; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..421
FT                   /note="Actin-like protein ARP6"
FT                   /id="PRO_0000089113"
SQ   SEQUENCE   421 AA;  48032 MW;  2865EBE5502BB8A0 CRC64;
     MTADQAIVID NGSYQVKFGL ASEVRPRVAL NALAKDKYGV THLSNQVQNI KDISSVVFRR
     PHELGQLTSW ELESCIWDYC LYNPDEFGID WQSLENRHVV LSETCMTLPE LSKNTDQVLF
     EEYEVDSLYK APTAAYIPFY TTNENIKTIS GKSDHGELDI EEKIEAGKEY NDFSLVIDSG
     FNCTWVIPIV KGVPYYKAVK KLDVGGRFLN GLLKETISFR HYNVMDESIL VNNIKEQCLY
     VDPVSYFEAF KAKGKNKIDF VLPDFQTSFQ GYVRDPKTAL PDNAQILTLT DERFSVPEAF
     FHPEISQSLK PGIIETVLES IYMLPELLRP LMASNIVCMG GNFNLPGFTD RLVSELQRQL
     PTDWVCRAKI SSGDKSLTGW TAMAKFAHTD AYKKARVTKE DYFEHGLDWT TKERFGYQNW
     V