ID   NUR1_CANGA              Reviewed;         438 AA.
AC   Q6FL09;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Nuclear rim protein 1;
GN   Name=NUR1; OrderedLocusNames=CAGL0L07084g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Member of a perinuclear network that controls recombination
CC       at multiple loci to maintain genome stability. Required for rDNA repeat
CC       stability (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NUR1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR380958; CAG62055.1; -; Genomic_DNA.
DR   RefSeq; XP_449085.1; XM_449085.1.
DR   AlphaFoldDB; Q6FL09; -.
DR   STRING; 5478.XP_449085.1; -.
DR   EnsemblFungi; CAG62055; CAG62055; CAGL0L07084g.
DR   GeneID; 2890830; -.
DR   KEGG; cgr:CAGL0L07084g; -.
DR   CGD; CAL0136192; CAGL0L07084g.
DR   VEuPathDB; FungiDB:CAGL0L07084g; -.
DR   eggNOG; ENOG502S7S0; Eukaryota.
DR   HOGENOM; CLU_625555_0_0_1; -.
DR   InParanoid; Q6FL09; -.
DR   OMA; LENTHWS; -.
DR   Proteomes; UP000002428; Chromosome L.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018819; Nur1/Mug154.
DR   PANTHER; PTHR28293; PTHR28293; 1.
DR   Pfam; PF10332; DUF2418; 1.
PE   3: Inferred from homology;
KW   Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..438
FT                   /note="Nuclear rim protein 1"
FT                   /id="PRO_0000409028"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          405..438
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        405..429
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   438 AA;  51561 MW;  8FDA3BB3FA7A6B7D CRC64;
     MFSWLIPDIP ELFLTISVWF RLQGWEDNTK LGFIIGNTLT TIFYILRLAQ DTLLAGVSRK
     LIRDYELFDL SKSETLLSDP AFSSYHDVLF NKHHSTANAS SYNKRVRKVT STVYWSTYFL
     LLLSCYTCYR LFNTYKVYRI YYLKDLNLDK HPSLKKIEPD YEVDEKLLKT SLKSKLLSRF
     IRLLQLQDEV ETELPKVTEH YTLNKWDPSK LIISLSTSFS PTIIICLMYT NVTFLTVIPI
     IIHQGIFYFM IWNRYEERFK DDALLMRENY LQYDTKYVKP LKQIMYQDVM TDTATISDGG
     FTKFFPVSKS TLFKHHEMSG DVIIERYNKK SREFENVTDI IKPHHHINNT VKILPPTIRK
     DHKTNRYDHR QQSILKDRKF NIDSNEPQII NALTTAIPSR SFFNNNPSGS NDDNCSGIKV
     RSSPTRETFF PATPLRKK