ID   NUR1_VANPO              Reviewed;         401 AA.
AC   A7TH24;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Nuclear rim protein 1;
GN   Name=NUR1; ORFNames=Kpol_1032p72;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Member of a perinuclear network that controls recombination
CC       at multiple loci to maintain genome stability. Required for rDNA repeat
CC       stability (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NUR1 family. {ECO:0000305}.
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DR   EMBL; DS480389; EDO18476.1; -; Genomic_DNA.
DR   RefSeq; XP_001646334.1; XM_001646284.1.
DR   AlphaFoldDB; A7TH24; -.
DR   STRING; 436907.A7TH24; -.
DR   EnsemblFungi; EDO18476; EDO18476; Kpol_1032p72.
DR   GeneID; 5546763; -.
DR   KEGG; vpo:Kpol_1032p72; -.
DR   eggNOG; ENOG502S7S0; Eukaryota.
DR   HOGENOM; CLU_033252_1_0_1; -.
DR   InParanoid; A7TH24; -.
DR   OMA; LENTHWS; -.
DR   OrthoDB; 896779at2759; -.
DR   PhylomeDB; A7TH24; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018819; Nur1/Mug154.
DR   PANTHER; PTHR28293; PTHR28293; 1.
DR   Pfam; PF10332; DUF2418; 1.
PE   3: Inferred from homology;
KW   Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..401
FT                   /note="Nuclear rim protein 1"
FT                   /id="PRO_0000409031"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        256..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   401 AA;  47397 MW;  C41C4A108BA1E248 CRC64;
     MNGLDDENQI DERDHYTDDG DYEIDIDSMN MFKSLYYEMM AYFSDLQMHL GEHLMAIDWD
     MKCKSIAEPV GNCLTALFYI IRLLQDTLLS NYKDVYVSTE AFDLSKSTTL QEFPFLIRFV
     EVSKTKNLQN AKYIKKKTFM FYFDKLLLFL MILILSTNAY ISWTFIWRNF KTYSLLYVVD
     RPNSKNVTKC SRTDLDQSYM ENVSYGSYWT MLSYYIRNFR KKDDLEDEIT TVKQKTPNVN
     EKDYYYQLKK WSPSKFLTSL FCSFSPTCLV FLILSDVSFT TSIAVILHQF IFKYVVFEGY
     ESRINDESII HSAMISEINQ KFVEPRLSKK VQDAKIDATP EGKVYRTEFF PSLTNCKSNL
     FNRHDLKGRS ITESYNDRIK EFEIVTNTNN ETHNVIKVVK K