NUSA_METJA
ID NUSA_METJA Reviewed; 183 AA.
AC Q58447;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Probable transcription termination protein NusA {ECO:0000255|HAMAP-Rule:MF_00945};
GN Name=nusA {ECO:0000255|HAMAP-Rule:MF_00945}; OrderedLocusNames=MJ1045;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
CC -!- FUNCTION: Participates in transcription termination.
CC {ECO:0000255|HAMAP-Rule:MF_00945}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00945}.
CC -!- SIMILARITY: Belongs to the NusA family. {ECO:0000255|HAMAP-
CC Rule:MF_00945}.
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DR EMBL; L77117; AAB99049.1; -; Genomic_DNA.
DR PIR; D64430; D64430.
DR RefSeq; WP_010870558.1; NC_000909.1.
DR AlphaFoldDB; Q58447; -.
DR SMR; Q58447; -.
DR STRING; 243232.MJ_1045; -.
DR EnsemblBacteria; AAB99049; AAB99049; MJ_1045.
DR GeneID; 1451942; -.
DR KEGG; mja:MJ_1045; -.
DR eggNOG; arCOG01760; Archaea.
DR HOGENOM; CLU_131906_1_0_2; -.
DR InParanoid; Q58447; -.
DR OMA; TDQIKYI; -.
DR OrthoDB; 99842at2157; -.
DR PhylomeDB; Q58447; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0031564; P:transcription antitermination; IBA:GO_Central.
DR Gene3D; 3.30.300.20; -; 2.
DR HAMAP; MF_00945_A; NusA_A; 1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR025249; KH_dom_NusA-like.
DR InterPro; IPR009019; KH_sf_prok-type.
DR InterPro; IPR010212; NusA_arc.
DR InterPro; IPR030842; NusA_bac.
DR PANTHER; PTHR22648; PTHR22648; 1.
DR Pfam; PF13184; KH_5; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54814; SSF54814; 2.
DR TIGRFAMs; TIGR01952; nusA_arch; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; RNA-binding; Transcription;
KW Transcription regulation; Transcription termination.
FT CHAIN 1..183
FT /note="Probable transcription termination protein NusA"
FT /id="PRO_0000181983"
FT DOMAIN 32..98
FT /note="KH"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00945"
FT REGION 149..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..183
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 183 AA; 21135 MW; 2845502CAD695783 CRC64;
MAKVRLTTEE IMKIGFFEKI ANVPILDCVL NDERVAFIVK EGDVGAAIGK GGENVKTAEE
KFGKKVDIIE YSDDWRKFIR NIFAPIQLDD VWVKRVGKDV VAFIKINPKV RRAVFGEKGK
NLERALKILK RHTKITKIKV IVENQKFKRK RAKRPVVKDQ QQEQTETKQE TDVQQDVKET
VKE
