ID   ARP6_EMENI              Reviewed;         479 AA.
AC   Q5AXH1; C8VC89;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Actin-like protein arp6;
GN   Name=arp6; ORFNames=AN7009;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC       dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC       transcriptional regulation of selected genes by chromatin remodeling.
CC       Involved in chromosome stability (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the SWR1 chromatin remodeling complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton
CC       {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the actin family. ARP6 subfamily. {ECO:0000305}.
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DR   EMBL; AACD01000117; EAA61655.1; -; Genomic_DNA.
DR   EMBL; BN001304; CBF79267.1; -; Genomic_DNA.
DR   RefSeq; XP_664613.1; XM_659521.1.
DR   AlphaFoldDB; Q5AXH1; -.
DR   SMR; Q5AXH1; -.
DR   STRING; 162425.CADANIAP00000467; -.
DR   PRIDE; Q5AXH1; -.
DR   EnsemblFungi; CBF79267; CBF79267; ANIA_07009.
DR   EnsemblFungi; EAA61655; EAA61655; AN7009.2.
DR   GeneID; 2869993; -.
DR   KEGG; ani:AN7009.2; -.
DR   VEuPathDB; FungiDB:AN7009; -.
DR   eggNOG; KOG0680; Eukaryota.
DR   HOGENOM; CLU_027965_1_1_1; -.
DR   InParanoid; Q5AXH1; -.
DR   OMA; FFEEYEC; -.
DR   OrthoDB; 649708at2759; -.
DR   Proteomes; UP000000560; Chromosome IV.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0000812; C:Swr1 complex; IBA:GO_Central.
DR   GO; GO:0031491; F:nucleosome binding; IBA:GO_Central.
DR   GO; GO:0043486; P:histone exchange; IBA:GO_Central.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR030054; Arp6.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   PANTHER; PTHR11937:SF47; PTHR11937:SF47; 1.
DR   Pfam; PF00022; Actin; 1.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
PE   3: Inferred from homology;
KW   Activator; Chromatin regulator; Cytoplasm; Cytoskeleton; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..479
FT                   /note="Actin-like protein arp6"
FT                   /id="PRO_0000089116"
SQ   SEQUENCE   479 AA;  53204 MW;  8BADBBC3DB4659CC CRC64;
     MGSTKPRPSG KNSISHAQSL PGKTFIIDNG AYNMKAGYAP DSQPLDDEEI ALSACAAIPN
     AIVKTRANRT YVGAQIGTNV TDWNEMLFRR PVEKGYTVNW EAQKEIWENS FFDERTVRSK
     ELHIADPEDV TIIFTEAPNA LPALQKNADE IIMEEWGFGG YLRCVVGMAK PFALNTGPSL
     NAWNEIQSLF EDSVLSQPRA VASPAECLLV VDSGYSHTVI TPVYRGRPLQ RGIRRLDLGG
     KHLTNYLKEL VSMRQYNMVD ETYIMNEVKE SVCFVSNDFN RDLERTWKGN RKRGQPDPTD
     GVVVDYVLPD PNGGKRGFMR PHDPLLGSKK RKAVLAGASA EQLNEDVLVL GNERFTVPEI
     LFTPSDIGMK SAGIPDIILQ SLSVLPTGLH PAFLANVLVV GGNSLLPGFM ERLETELRQI
     ASAECVVRVR RPKDPIRFAW LGGSRLATNK EELKKVAITR QEYQEHGSSW TTRKFSGAL