ID   NUSB_BORAP              Reviewed;         137 AA.
AC   Q0SP57; G0IQV2;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   OrderedLocusNames=BAPKO_0108, BafPKo_0105;
OS   Borreliella afzelii (strain PKo) (Borrelia afzelii).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=390236;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PKo;
RX   PubMed=16914037; DOI=10.1186/1471-2164-7-211;
RA   Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J.,
RA   Wilske B., Platzer M.;
RT   "Comparative genome analysis: selection pressure on the Borrelia vls
RT   cassettes is essential for infectivity.";
RL   BMC Genomics 7:211-211(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PKo;
RX   PubMed=22123755; DOI=10.1128/jb.05951-11;
RA   Casjens S.R., Mongodin E.F., Qiu W.G., Dunn J.J., Luft B.J.,
RA   Fraser-Liggett C.M., Schutzer S.E.;
RT   "Whole-genome sequences of two Borrelia afzelii and two Borrelia garinii
RT   Lyme disease agent isolates.";
RL   J. Bacteriol. 193:6995-6996(2011).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
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DR   EMBL; CP000395; ABH01371.1; -; Genomic_DNA.
DR   EMBL; CP002933; AEL69338.1; -; Genomic_DNA.
DR   RefSeq; WP_011600838.1; NC_017238.1.
DR   AlphaFoldDB; Q0SP57; -.
DR   SMR; Q0SP57; -.
DR   STRING; 390236.BafPKo_0105; -.
DR   EnsemblBacteria; AEL69338; AEL69338; BafPKo_0105.
DR   KEGG; baf:BAPKO_0108; -.
DR   KEGG; bafz:BafPKo_0105; -.
DR   PATRIC; fig|390236.22.peg.104; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_087843_3_1_12; -.
DR   OMA; DRMPVVD; -.
DR   OrthoDB; 1574817at2; -.
DR   Proteomes; UP000005216; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Transcription; Transcription antitermination;
KW   Transcription regulation.
FT   CHAIN           1..137
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000265491"
SQ   SEQUENCE   137 AA;  15833 MW;  CDC7FC4B0913AA9A CRC64;
     MHEVRVLAFQ KIYSIDINQS AMDDIFDIFN IEDKGLDIEN ESIKSFYSSL VNGTFNNLEH
     IDSLIRDISW NWSLDRMDKV DLAILRMGVY SLKFQNFENS KRAVIDDAIL IAKKYGSKNS
     CKFINGILDA LLKNMEN