ID   NUSB_BRUSU              Reviewed;         171 AA.
AC   Q8G1E7; G0K8I9;
DT   20-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   OrderedLocusNames=BR0770, BS1330_I0766;
OS   Brucella suis biovar 1 (strain 1330).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=204722;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1330;
RX   PubMed=12271122; DOI=10.1073/pnas.192319099;
RA   Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA   Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA   Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA   Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA   Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA   Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT   "The Brucella suis genome reveals fundamental similarities between animal
RT   and plant pathogens and symbionts.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1330;
RX   PubMed=22038969; DOI=10.1128/jb.06181-11;
RA   Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT   "Revised genome sequence of Brucella suis 1330.";
RL   J. Bacteriol. 193:6410-6410(2011).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
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DR   EMBL; AE014291; AAN29699.1; -; Genomic_DNA.
DR   EMBL; CP002997; AEM18116.1; -; Genomic_DNA.
DR   RefSeq; WP_004688221.1; NZ_KN046804.1.
DR   AlphaFoldDB; Q8G1E7; -.
DR   SMR; Q8G1E7; -.
DR   EnsemblBacteria; AEM18116; AEM18116; BS1330_I0766.
DR   GeneID; 45124207; -.
DR   GeneID; 55590484; -.
DR   KEGG; bms:BR0770; -.
DR   KEGG; bsi:BS1330_I0766; -.
DR   PATRIC; fig|204722.21.peg.2648; -.
DR   HOGENOM; CLU_087843_4_0_5; -.
DR   OMA; LYQMDIA; -.
DR   PhylomeDB; Q8G1E7; -.
DR   Proteomes; UP000007104; Chromosome I.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Transcription; Transcription antitermination;
KW   Transcription regulation.
FT   CHAIN           1..171
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000176516"
SQ   SEQUENCE   171 AA;  18967 MW;  D8F0877A29A55DFC CRC64;
     MNSIPEGRPT PNLPRTANKR GVARLAAVQA LYQMDVAGTG VMEVVAEYEA FRLGKEVDGT
     QYLDADPQWF RAIVAGVVED QLKLDPMIHQ ALTEDWPLSR LDSTLRAILR AGAWELKARK
     DVPTAVIVSE YVDIAKAFYT EDEPKLVNAV LDRLALVIRG ESRGAKPRHK S