NUSB_BURTA
ID NUSB_BURTA Reviewed; 145 AA.
AC Q2SYC5;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=BTH_I1529;
OS Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 /
OS E264).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=271848;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264;
RX PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA DeShazer D.;
RT "Bacterial genome adaptation to niches: divergence of the potential
RT virulence genes in three Burkholderia species of different survival
RT strategies.";
RL BMC Genomics 6:174-174(2005).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000086; ABC36303.1; -; Genomic_DNA.
DR RefSeq; WP_004185707.1; NZ_CP008785.1.
DR PDB; 6CKQ; NMR; -; A=1-145.
DR PDBsum; 6CKQ; -.
DR AlphaFoldDB; Q2SYC5; -.
DR BMRB; Q2SYC5; -.
DR SMR; Q2SYC5; -.
DR PRIDE; Q2SYC5; -.
DR EnsemblBacteria; ABC36303; ABC36303; BTH_I1529.
DR GeneID; 56594848; -.
DR KEGG; bte:BTH_I1529; -.
DR HOGENOM; CLU_087843_4_1_4; -.
DR OMA; DRMPVVD; -.
DR OrthoDB; 1574817at2; -.
DR Proteomes; UP000001930; Chromosome I.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; -; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR PANTHER; PTHR11078; PTHR11078; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; SSF48013; 1.
DR TIGRFAMs; TIGR01951; nusB; 1.
PE 1: Evidence at protein level;
KW 3D-structure; RNA-binding; Transcription; Transcription antitermination;
KW Transcription regulation.
FT CHAIN 1..145
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_0000265499"
FT STRAND 1..3
FT /evidence="ECO:0007829|PDB:6CKQ"
FT HELIX 6..23
FT /evidence="ECO:0007829|PDB:6CKQ"
FT HELIX 27..36
FT /evidence="ECO:0007829|PDB:6CKQ"
FT HELIX 39..42
FT /evidence="ECO:0007829|PDB:6CKQ"
FT HELIX 47..69
FT /evidence="ECO:0007829|PDB:6CKQ"
FT STRAND 70..72
FT /evidence="ECO:0007829|PDB:6CKQ"
FT HELIX 74..76
FT /evidence="ECO:0007829|PDB:6CKQ"
FT HELIX 79..95
FT /evidence="ECO:0007829|PDB:6CKQ"
FT HELIX 100..114
FT /evidence="ECO:0007829|PDB:6CKQ"
FT HELIX 116..134
FT /evidence="ECO:0007829|PDB:6CKQ"
FT HELIX 136..139
FT /evidence="ECO:0007829|PDB:6CKQ"
SQ SEQUENCE 145 AA; 15981 MW; 9C669799DAE6F855 CRC64;
MKKSARRQSR ELATQGLYQW LLSNAAPGEI DAQLRGALGY DKADKTLLDT ILHGVIREHA
TLAEAISPSL DRPIDQLSPV ERAVLLIATY ELTHQIETPY RVIINEAVEL AKTFGGSDGY
KYVNGVLDKL AVKLRPAETQ ARRGA
