ID   NUSB_CUTAK              Reviewed;         261 AA.
AC   Q6A8H8;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=PPA1188;
OS   Cutibacterium acnes (strain DSM 16379 / KPA171202) (Propionibacterium
OS   acnes).
OC   Bacteria; Actinobacteria; Propionibacteriales; Propionibacteriaceae;
OC   Cutibacterium.
OX   NCBI_TaxID=267747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16379 / KPA171202;
RX   PubMed=15286373; DOI=10.1126/science.1100330;
RA   Brueggemann H., Henne A., Hoster F., Liesegang H., Wiezer A.,
RA   Strittmatter A., Hujer S., Duerre P., Gottschalk G.;
RT   "The complete genome sequence of Propionibacterium acnes, a commensal of
RT   human skin.";
RL   Science 305:671-673(2004).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
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DR   EMBL; AE017283; AAT82937.1; -; Genomic_DNA.
DR   RefSeq; WP_002516819.1; NZ_CP025935.1.
DR   AlphaFoldDB; Q6A8H8; -.
DR   SMR; Q6A8H8; -.
DR   STRING; 267747.PPA1188; -.
DR   EnsemblBacteria; AAT82937; AAT82937; PPA1188.
DR   GeneID; 66620949; -.
DR   KEGG; pac:PPA1188; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_087843_2_1_11; -.
DR   OMA; RREIDYM; -.
DR   Proteomes; UP000000603; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Transcription; Transcription antitermination;
KW   Transcription regulation.
FT   CHAIN           1..261
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000265560"
FT   REGION          168..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        199..230
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        234..261
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   261 AA;  27600 MW;  84FAB3EFAD571C29 CRC64;
     MSTNTVPTPD DEGPTEWIGD LEVRRVSGDI QEHADLSTRS KARKQALDIL FEADLIGTDP
     LEVLAARPGV FTNPVRPFAA DLVRGVAATQ VGLDSVLTDC LSEGWTLARM PRVDRILARL
     GAFEILHTDT PNPAVISEAI ELSEEFSTDD SAPFLNGLLG AVITHGPARV EDQPSDDAAS
     LTCPAPDGGS EQPPITVDDV GSMASSSDSF PAEVGNVDTT SGNASDPENS ADDFELTGGE
     HPTSKDHELA TDLHKKDTTD D