NUSB_DEHMC
ID NUSB_DEHMC Reviewed; 143 AA.
AC Q3ZYI9;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2005, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=cbdbA1206;
OS Dehalococcoides mccartyi (strain CBDB1).
OC Bacteria; Chloroflexi; Dehalococcoidia; Dehalococcoidales;
OC Dehalococcoidaceae; Dehalococcoides.
OX NCBI_TaxID=255470;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBDB1;
RX PubMed=16116419; DOI=10.1038/nbt1131;
RA Kube M., Beck A., Zinder S.H., Kuhl H., Reinhardt R., Adrian L.;
RT "Genome sequence of the chlorinated compound-respiring bacterium
RT Dehalococcoides species strain CBDB1.";
RL Nat. Biotechnol. 23:1269-1273(2005).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
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DR EMBL; AJ965256; CAI83285.1; -; Genomic_DNA.
DR RefSeq; WP_011309636.1; NC_007356.1.
DR AlphaFoldDB; Q3ZYI9; -.
DR SMR; Q3ZYI9; -.
DR KEGG; deh:cbdbA1206; -.
DR HOGENOM; CLU_087843_3_3_0; -.
DR OMA; MKTYRRQ; -.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; -; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR PANTHER; PTHR11078; PTHR11078; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; SSF48013; 1.
DR TIGRFAMs; TIGR01951; nusB; 1.
PE 3: Inferred from homology;
KW RNA-binding; Transcription; Transcription antitermination;
KW Transcription regulation.
FT CHAIN 1..143
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_0000265513"
SQ SEQUENCE 143 AA; 16162 MW; C001B0C76E0FB73D CRC64;
MTTSRRKARE IVLQALYEQD LAGHNAEDVL KRLLTENPQT EENVEFIFRL TNAVVKHKDL
LDENIRQFAS AWPVEQLSYI DRNVLRLAIF EIIHENDVPV KVAINEAVEL AKSFGGNSSA
RFINGVLSSV SKALADTANQ REE