NUSB_DEIDV
ID NUSB_DEIDV Reviewed; 168 AA.
AC C1CVC5;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=Deide_12270;
OS Deinococcus deserti (strain DSM 17065 / CIP 109153 / LMG 22923 / VCD115).
OC Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=546414;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17065 / CIP 109153 / LMG 22923 / VCD115;
RX PubMed=19370165; DOI=10.1371/journal.pgen.1000434;
RA de Groot A., Dulermo R., Ortet P., Blanchard L., Guerin P., Fernandez B.,
RA Vacherie B., Dossat C., Jolivet E., Siguier P., Chandler M., Barakat M.,
RA Dedieu A., Barbe V., Heulin T., Sommer S., Achouak W., Armengaud J.;
RT "Alliance of proteomics and genomics to unravel the specificities of Sahara
RT bacterium Deinococcus deserti.";
RL PLoS Genet. 5:E1000434-E1000434(2009).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
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DR EMBL; CP001114; ACO46142.1; -; Genomic_DNA.
DR RefSeq; WP_012693265.1; NC_012526.1.
DR AlphaFoldDB; C1CVC5; -.
DR SMR; C1CVC5; -.
DR STRING; 546414.Deide_12270; -.
DR PaxDb; C1CVC5; -.
DR EnsemblBacteria; ACO46142; ACO46142; Deide_12270.
DR KEGG; ddr:Deide_12270; -.
DR eggNOG; COG0781; Bacteria.
DR HOGENOM; CLU_087843_3_0_0; -.
DR OMA; DRMPVVD; -.
DR OrthoDB; 1574817at2; -.
DR Proteomes; UP000002208; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; -; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR PANTHER; PTHR11078; PTHR11078; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; SSF48013; 1.
DR TIGRFAMs; TIGR01951; nusB; 1.
PE 3: Inferred from homology;
KW Reference proteome; RNA-binding; Transcription;
KW Transcription antitermination; Transcription regulation.
FT CHAIN 1..168
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_1000202475"
SQ SEQUENCE 168 AA; 18666 MW; 63E76EA2C6AD412F CRC64;
MTRRREKAVQ PVGTRRAARE FVFRVLFEAD RGDLPLDTVF TRAEGAMREG DDTFPQLSAD
ALTFANELVR GLEKHRADID TTLRRTIRGW SFDQMAQTDL NVLRLATFEL IYTAEPHPPV
IESAVRIARK FGGDDSGRFV NGVLAGLSRS LQSAGVAKAD EQADTAQD