NUSB_DEIRA
ID NUSB_DEIRA Reviewed; 192 AA.
AC Q9RSQ7;
DT 02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=DR_2067;
OS Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG
OS 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
OC Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=243230;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC 9279 / R1 / VKM B-1422;
RX PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA Fraser C.M.;
RT "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT R1.";
RL Science 286:1571-1577(1999).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
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DR EMBL; AE000513; AAF11617.1; -; Genomic_DNA.
DR PIR; E75318; E75318.
DR RefSeq; NP_295790.1; NC_001263.1.
DR RefSeq; WP_010888698.1; NZ_CP015081.1.
DR AlphaFoldDB; Q9RSQ7; -.
DR SMR; Q9RSQ7; -.
DR STRING; 243230.DR_2067; -.
DR EnsemblBacteria; AAF11617; AAF11617; DR_2067.
DR KEGG; dra:DR_2067; -.
DR PATRIC; fig|243230.17.peg.2292; -.
DR eggNOG; COG0781; Bacteria.
DR HOGENOM; CLU_087843_3_0_0; -.
DR InParanoid; Q9RSQ7; -.
DR OMA; DRMPVVD; -.
DR OrthoDB; 1574817at2; -.
DR Proteomes; UP000002524; Chromosome I.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; -; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR PANTHER; PTHR11078; PTHR11078; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; SSF48013; 1.
DR TIGRFAMs; TIGR01951; nusB; 1.
PE 3: Inferred from homology;
KW Reference proteome; RNA-binding; Transcription;
KW Transcription antitermination; Transcription regulation.
FT CHAIN 1..192
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_0000176535"
FT REGION 154..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 192 AA; 21148 MW; 8401B62C0B31B4C7 CRC64;
MTRRREKAVQ PVGTRRAARE FVFRVLFEAD RGDVPLQAVF TRAEGVMREG DDTFPQLGPD
ALHFAEELVT GLERHREAID DVLHRTIRGW TFDQMAQTDL NVLRLATYEL MYTPEPHPPV
IESAVRIARK FGGDDSGRFV NGVLAGLSRN LREEVGESPA ADMTAPAPAD TAPADTAPAD
PAASEPDEPR DA
