ID   NUSB_LACLA              Reviewed;         192 AA.
AC   Q9CHN4;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 2.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=LL0694;
GN   ORFNames=L92686;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK04792.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE005176; AAK04792.1; ALT_INIT; Genomic_DNA.
DR   PIR; F86711; F86711.
DR   RefSeq; NP_266850.1; NC_002662.1.
DR   AlphaFoldDB; Q9CHN4; -.
DR   SMR; Q9CHN4; -.
DR   STRING; 272623.L92686; -.
DR   PaxDb; Q9CHN4; -.
DR   EnsemblBacteria; AAK04792; AAK04792; L92686.
DR   KEGG; lla:L92686; -.
DR   PATRIC; fig|272623.7.peg.745; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_857344_0_0_9; -.
DR   OMA; YQEAMVP; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   Reference proteome; RNA-binding; Transcription;
KW   Transcription antitermination; Transcription regulation.
FT   CHAIN           1..192
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000176547"
SQ   SEQUENCE   192 AA;  22138 MW;  F82A25722E028426 CRC64;
     MFQIELDEEP VAPKVLEFFK NLPENATAEQ SLETFQKTFS FLHENVLEKY TSDLFTPSTL
     KEELDEQLAQ AENNAQSQLS ELLKNTKRFV LNYDNDRPED LEAPEYFTQL VDGVLDKKED
     LEANISKYLT KTWSFSRLTL VEQAILQVSS YEILYTETPD VVAVNEAVEL SKDFSDEKSS
     RFINGVLTNF LK