ID   NUSB_NOCFA              Reviewed;         169 AA.
AC   Q5YTL2;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=NFA_36310;
OS   Nocardia farcinica (strain IFM 10152).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia.
OX   NCBI_TaxID=247156;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 10152;
RX   PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA   Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA   Shiba T., Hattori M.;
RT   "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
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DR   EMBL; AP006618; BAD58479.1; -; Genomic_DNA.
DR   RefSeq; WP_011210164.1; NC_006361.1.
DR   AlphaFoldDB; Q5YTL2; -.
DR   SMR; Q5YTL2; -.
DR   STRING; 247156.NFA_36310; -.
DR   EnsemblBacteria; BAD58479; BAD58479; NFA_36310.
DR   GeneID; 61134327; -.
DR   KEGG; nfa:NFA_36310; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_087843_2_3_11; -.
DR   OMA; DRMPVVD; -.
DR   Proteomes; UP000006820; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   Reference proteome; RNA-binding; Transcription;
KW   Transcription antitermination; Transcription regulation.
FT   CHAIN           1..169
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000265554"
SQ   SEQUENCE   169 AA;  18464 MW;  BC692CE7A9C32800 CRC64;
     MAEQPADKKS TFKKLGARHK ARRRAVDLLF EAEARDVDAA DLLTERADLA TRDQSVAPLH
     AYTRTLVEGV ADELERVDGT IESYLQDWTL SRLPAVDRAI LRVAVWELFH ATDVPPVVAV
     DEAVELAKEL STDDSPSFVN GVLGQVVLVA PQVRAAAAAT RAPRQEPEA