NUSB_PSEAE
ID NUSB_PSEAE Reviewed; 159 AA.
AC Q9HWX6;
DT 02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=PA4052;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
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DR EMBL; AE004091; AAG07439.1; -; Genomic_DNA.
DR PIR; G83140; G83140.
DR RefSeq; NP_252741.1; NC_002516.2.
DR RefSeq; WP_003093308.1; NZ_QZGE01000013.1.
DR AlphaFoldDB; Q9HWX6; -.
DR SMR; Q9HWX6; -.
DR STRING; 287.DR97_3815; -.
DR PaxDb; Q9HWX6; -.
DR PRIDE; Q9HWX6; -.
DR DNASU; 878643; -.
DR EnsemblBacteria; AAG07439; AAG07439; PA4052.
DR GeneID; 878643; -.
DR KEGG; pae:PA4052; -.
DR PATRIC; fig|208964.12.peg.4243; -.
DR PseudoCAP; PA4052; -.
DR HOGENOM; CLU_087843_4_1_6; -.
DR InParanoid; Q9HWX6; -.
DR OMA; DRMPVVD; -.
DR PhylomeDB; Q9HWX6; -.
DR BioCyc; PAER208964:G1FZ6-4125-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; -; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR PANTHER; PTHR11078; PTHR11078; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; SSF48013; 1.
DR TIGRFAMs; TIGR01951; nusB; 1.
PE 3: Inferred from homology;
KW Reference proteome; RNA-binding; Transcription;
KW Transcription antitermination; Transcription regulation.
FT CHAIN 1..159
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_0000176564"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 159 AA; 17707 MW; A48B3ED5531A1C11 CRC64;
MSNQDSGNPA AKPPKGKTAA RRKARSLAVQ ALYSWQIAGQ PLHEIEAQFR TDNDFSEVDG
AYFHEILHGV PRQKSELDST FEPCLDRPLA EIDPVELAIL RLSTYELRNR IDVPYKVVIN
EGIELAKTFG ATDGHKFVNG VLDKLAPRLR AAELRGGKR
