NUSB_PSYA2
ID NUSB_PSYA2 Reviewed; 375 AA.
AC Q4FPZ1;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=Psyc_2070;
OS Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Psychrobacter.
OX NCBI_TaxID=259536;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17307 / VKM B-2377 / 273-4;
RX PubMed=20154119; DOI=10.1128/aem.02101-09;
RA Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N.,
RA Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C.,
RA Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P.,
RA Murray A., Thomashow M., Tiedje J.M.;
RT "The genome sequence of Psychrobacter arcticus 273-4, a psychroactive
RT Siberian permafrost bacterium, reveals mechanisms for adaptation to low-
RT temperature growth.";
RL Appl. Environ. Microbiol. 76:2304-2312(2010).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
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DR EMBL; CP000082; AAZ19917.1; -; Genomic_DNA.
DR RefSeq; WP_011281324.1; NC_007204.1.
DR AlphaFoldDB; Q4FPZ1; -.
DR SMR; Q4FPZ1; -.
DR STRING; 259536.Psyc_2070; -.
DR EnsemblBacteria; AAZ19917; AAZ19917; Psyc_2070.
DR KEGG; par:Psyc_2070; -.
DR eggNOG; COG0781; Bacteria.
DR HOGENOM; CLU_882419_0_0_6; -.
DR OMA; HEMMRDI; -.
DR OrthoDB; 1574817at2; -.
DR Proteomes; UP000000546; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; -; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; SSF48013; 1.
DR TIGRFAMs; TIGR01951; nusB; 1.
PE 3: Inferred from homology;
KW Reference proteome; RNA-binding; Transcription;
KW Transcription antitermination; Transcription regulation.
FT CHAIN 1..375
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_0000265567"
FT REGION 25..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 375 AA; 41193 MW; 367749526F8BA97E CRC64;
MTDQLKRAIS AAQTAQINDQ QAEATRIASS SAGDQTFDMS ESSYKTSHTA IRKARRFAMQ
GLYEWLVTDR RFDIDGKLGW KANAPHDIAA RTRATNAMHT VHIGYYHEMM RDIPEQIDAL
NTLITQQLDR EINKLDTVEH AILLIGAYEL QNRLEIPYKV VLDEAMKLNN HFGATDAHKL
INAVLDRMAV ELRAPEIEAD SKANLRTSQK AAAKPALKTD NSTNNNADID TTTVAEKPTA
SNKPRISANN TSVKRNSASK ALANISDYKA SKQNDAQNMV EESIIKPASI EPVIADKANA
FAASAENIVN HQPVEENVPA SNDVNDNTTS LAEVELLDSN SVDVDIKGVD IKNIDVKEDA
SESVELNDAD AKNQD