NUSB_RICPR
ID NUSB_RICPR Reviewed; 155 AA.
AC Q9ZE01;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 31-JAN-2002, sequence version 2.
DT 25-MAY-2022, entry version 101.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=RP162;
OS Rickettsia prowazekii (strain Madrid E).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX NCBI_TaxID=272947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Madrid E;
RX PubMed=9823893; DOI=10.1038/24094;
RA Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA Kurland C.G.;
RT "The genome sequence of Rickettsia prowazekii and the origin of
RT mitochondria.";
RL Nature 396:133-140(1998).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073, ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA14629.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AJ235270; CAA14629.1; ALT_INIT; Genomic_DNA.
DR PIR; F71726; F71726.
DR RefSeq; NP_220552.1; NC_000963.1.
DR RefSeq; WP_014411647.1; NC_000963.1.
DR AlphaFoldDB; Q9ZE01; -.
DR SMR; Q9ZE01; -.
DR STRING; 272947.RP162; -.
DR EnsemblBacteria; CAA14629; CAA14629; CAA14629.
DR GeneID; 57569291; -.
DR KEGG; rpr:RP162; -.
DR PATRIC; fig|272947.5.peg.166; -.
DR eggNOG; COG0781; Bacteria.
DR HOGENOM; CLU_087843_4_3_5; -.
DR Proteomes; UP000002480; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; -; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR PANTHER; PTHR11078; PTHR11078; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; SSF48013; 1.
DR TIGRFAMs; TIGR01951; nusB; 1.
PE 3: Inferred from homology;
KW Reference proteome; RNA-binding; Transcription;
KW Transcription antitermination; Transcription regulation.
FT CHAIN 1..155
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_0000176572"
SQ SEQUENCE 155 AA; 17652 MW; B69F86311680A401 CRC64;
MSTNKINKKS IARIAAVQAL YQNILQNNYD MYDIMQNILA CYHSNNSIDL PKNFKISLSI
SHFKMLVKSV FENINKLDEI IDNHLTNAKD SVHMPILLRA LLRVSICELL FCSTTPAKVV
INEYTDIAND LLNEHEIGFV NSILDKIAQE NNKIS