ID   NUSB_RICTY              Reviewed;         154 AA.
AC   Q68XK6;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=RT0152;
OS   Rickettsia typhi (strain ATCC VR-144 / Wilmington).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=257363;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-144 / Wilmington;
RX   PubMed=15317790; DOI=10.1128/jb.186.17.5842-5855.2004;
RA   McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E.,
RA   McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E.,
RA   Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C.,
RA   Yu X.-J., Walker D.H., Weinstock G.M.;
RT   "Complete genome sequence of Rickettsia typhi and comparison with sequences
RT   of other Rickettsiae.";
RL   J. Bacteriol. 186:5842-5855(2004).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAU03636.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE017197; AAU03636.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_014419403.1; NC_006142.1.
DR   AlphaFoldDB; Q68XK6; -.
DR   SMR; Q68XK6; -.
DR   STRING; 257363.RT0152; -.
DR   EnsemblBacteria; AAU03636; AAU03636; RT0152.
DR   KEGG; rty:RT0152; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_087843_4_3_5; -.
DR   OMA; LYQMDIA; -.
DR   OrthoDB; 1574817at2; -.
DR   Proteomes; UP000000604; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Transcription; Transcription antitermination;
KW   Transcription regulation.
FT   CHAIN           1..154
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000265582"
SQ   SEQUENCE   154 AA;  17592 MW;  0562BDFFE55C5452 CRC64;
     MSTNKINKKS IARIAAVQAL YQNILQNNYD MYDIMQNILA CYHSNSIDLP KNFKISLSIS
     HFKMLVKSVF ENINKLDEII DNHLTNDKDP VHMPILLRAL LRVSICELLF CSTTPAKVVI
     NEYTDIANDL LNEHEIGFVN SILDKIAQEN NKIS