ID   NUSB_STAA8              Reviewed;         129 AA.
AC   Q2FY45;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   OrderedLocusNames=SAOUHSC_01621;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000253; ABD30699.1; -; Genomic_DNA.
DR   RefSeq; WP_000087385.1; NZ_LS483365.1.
DR   RefSeq; YP_500135.1; NC_007795.1.
DR   AlphaFoldDB; Q2FY45; -.
DR   SMR; Q2FY45; -.
DR   STRING; 1280.SAXN108_1548; -.
DR   EnsemblBacteria; ABD30699; ABD30699; SAOUHSC_01621.
DR   GeneID; 3919959; -.
DR   KEGG; sao:SAOUHSC_01621; -.
DR   PATRIC; fig|93061.5.peg.1475; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_087843_3_3_9; -.
DR   OMA; DRMPVVD; -.
DR   PRO; PR:Q2FY45; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   Reference proteome; RNA-binding; Transcription;
KW   Transcription antitermination; Transcription regulation.
FT   CHAIN           1..129
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000265598"
SQ   SEQUENCE   129 AA;  15061 MW;  FEA7E3CA3B6216AA CRC64;
     MSRKESRVQA FQTLFQLEMK DSDLTINEAI SFIKDDNPDL DFEFIHWLVS GVKDHEPVLD
     ETISPYLKDW TIARLLKTDR IILRMATYEI LHSDTPAKVV MNEAVELTKQ FSDDDHYKFI
     NGVLSNIKK