ID   NUSB_STAES              Reviewed;         129 AA.
AC   Q8CP37;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=SE_1205;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
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DR   EMBL; AE015929; AAO04804.1; -; Genomic_DNA.
DR   RefSeq; NP_764760.1; NC_004461.1.
DR   RefSeq; WP_001831090.1; NZ_WBME01000006.1.
DR   AlphaFoldDB; Q8CP37; -.
DR   SMR; Q8CP37; -.
DR   STRING; 176280.SE_1205; -.
DR   EnsemblBacteria; AAO04804; AAO04804; SE_1205.
DR   GeneID; 50018677; -.
DR   KEGG; sep:SE_1205; -.
DR   PATRIC; fig|176280.10.peg.1175; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_087843_3_3_9; -.
DR   OMA; DRMPVVD; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Transcription; Transcription antitermination;
KW   Transcription regulation.
FT   CHAIN           1..129
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000176583"
SQ   SEQUENCE   129 AA;  15150 MW;  161923DD8535A1CA CRC64;
     MSRKDARVQA FQTLFQLEIK ETDLTIQEAI EFIKDDHSDL DFDFIYWLVT GVKDHQIVLD
     ETIKPHLKDW SIDRLLKSDR IILRMATFEI LHSDTPKKVV VNEAVELTKQ FSDDDHYKFV
     NGVLSNIND