NUSB_SYMTH
ID NUSB_SYMTH Reviewed; 153 AA.
AC Q67NA9;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=STH1849;
OS Symbiobacterium thermophilum (strain T / IAM 14863).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Symbiobacteriaceae;
OC Symbiobacterium.
OX NCBI_TaxID=292459;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T / IAM 14863;
RX PubMed=15383646; DOI=10.1093/nar/gkh830;
RA Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K.,
RA Ikeda H., Hattori M., Beppu T.;
RT "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium
RT that depends on microbial commensalism.";
RL Nucleic Acids Res. 32:4937-4944(2004).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
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DR EMBL; AP006840; BAD40834.1; -; Genomic_DNA.
DR RefSeq; WP_011195977.1; NC_006177.1.
DR AlphaFoldDB; Q67NA9; -.
DR SMR; Q67NA9; -.
DR STRING; 292459.STH1849; -.
DR EnsemblBacteria; BAD40834; BAD40834; STH1849.
DR KEGG; sth:STH1849; -.
DR eggNOG; COG0781; Bacteria.
DR HOGENOM; CLU_087843_3_3_9; -.
DR OMA; DRMPVVD; -.
DR OrthoDB; 1574817at2; -.
DR Proteomes; UP000000417; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; -; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR PANTHER; PTHR11078; PTHR11078; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; SSF48013; 1.
DR TIGRFAMs; TIGR01951; nusB; 1.
PE 3: Inferred from homology;
KW Reference proteome; RNA-binding; Transcription;
KW Transcription antitermination; Transcription regulation.
FT CHAIN 1..153
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_0000265610"
SQ SEQUENCE 153 AA; 16960 MW; 29EF79ED34609E37 CRC64;
MSRRKARELA LQALFQMDIA GTDPDTAVAQ ALTRETEPDW APDRLEEESA EFARRLVRGA
WQHREESDRL IAQYARGWRV ERMAAVDRAI LRMAVYEIVH SEDVPDSVAV AEAVELAKTF
STADSSRFVN GILGSVIRGM KGAAGADEAV SRD
