ID   NUSB_THEAB              Reviewed;         142 AA.
AC   B7IH57;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=THA_962;
OS   Thermosipho africanus (strain TCF52B).
OC   Bacteria; Thermotogae; Thermotogales; Fervidobacteriaceae; Thermosipho.
OX   NCBI_TaxID=484019;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TCF52B;
RX   PubMed=19124572; DOI=10.1128/jb.01448-08;
RA   Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D.,
RA   Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F.;
RT   "The genome of Thermosipho africanus TCF52B: lateral genetic connections to
RT   the Firmicutes and Archaea.";
RL   J. Bacteriol. 191:1974-1978(2009).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
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DR   EMBL; CP001185; ACJ75421.1; -; Genomic_DNA.
DR   RefSeq; WP_012579905.1; NC_011653.1.
DR   AlphaFoldDB; B7IH57; -.
DR   SMR; B7IH57; -.
DR   STRING; 484019.THA_962; -.
DR   EnsemblBacteria; ACJ75421; ACJ75421; THA_962.
DR   KEGG; taf:THA_962; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_087843_3_3_0; -.
DR   OMA; TKQFCNL; -.
DR   OrthoDB; 1574817at2; -.
DR   Proteomes; UP000002453; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   Reference proteome; RNA-binding; Transcription;
KW   Transcription antitermination; Transcription regulation.
FT   CHAIN           1..142
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_1000117057"
SQ   SEQUENCE   142 AA;  16708 MW;  ADC3C65C7BA335C1 CRC64;
     MIKRRHKMRE SVFKALFQWD FQKDEDLTEI AKQHVSLLED EKLREQAYSY IEGIKKTIES
     LDEIISKYLQ NWTLDRLSVT DRNILRLGTY ELLYVDDVPI EVTLDEMIEL GKTYGTENSG
     KFVNGVLDRI AKGEAPKEKF DM