ID   NUSB_THEFY              Reviewed;         142 AA.
AC   Q47QY5;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=Tfu_1094;
OS   Thermobifida fusca (strain YX).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Thermobifida.
OX   NCBI_TaxID=269800;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YX;
RX   PubMed=17209016; DOI=10.1128/jb.01899-06;
RA   Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G.,
RA   Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B.,
RA   Kyrpides N.;
RT   "Genome sequence and analysis of the soil cellulolytic actinomycete
RT   Thermobifida fusca YX.";
RL   J. Bacteriol. 189:2477-2486(2007).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
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DR   EMBL; CP000088; AAZ55132.1; -; Genomic_DNA.
DR   RefSeq; WP_011291541.1; NC_007333.1.
DR   AlphaFoldDB; Q47QY5; -.
DR   SMR; Q47QY5; -.
DR   STRING; 269800.Tfu_1094; -.
DR   EnsemblBacteria; AAZ55132; AAZ55132; Tfu_1094.
DR   KEGG; tfu:Tfu_1094; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_087843_2_3_11; -.
DR   OMA; DRMPVVD; -.
DR   OrthoDB; 1574817at2; -.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Transcription; Transcription antitermination;
KW   Transcription regulation.
FT   CHAIN           1..142
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000265616"
SQ   SEQUENCE   142 AA;  16080 MW;  433CB7D2D6E3E9C5 CRC64;
     MGGSRRRGSR HKARVRAVEI LYEAEVRGVP VSEVIERRRA QTEPPINEFT EQLATRVDEH
     RARIDELLET YAIGWTLDRM PVVDRNILRI GVYELLWADD IPDGVAIAEA VAMAKELSTD
     ESPVFVNGLL SRLMEKKPSL SL