ID   NUSB_THET8              Reviewed;         151 AA.
AC   Q5SJ93;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=TTHA1121;
OS   Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX   NCBI_TaxID=300852;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27634 / DSM 579 / HB8;
RA   Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T.,
RA   Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.;
RT   "Complete genome sequence of Thermus thermophilus HB8.";
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073}.
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DR   EMBL; AP008226; BAD70944.1; -; Genomic_DNA.
DR   RefSeq; WP_008632549.1; NC_006461.1.
DR   RefSeq; YP_144387.1; NC_006461.1.
DR   AlphaFoldDB; Q5SJ93; -.
DR   SMR; Q5SJ93; -.
DR   STRING; 300852.55772503; -.
DR   EnsemblBacteria; BAD70944; BAD70944; BAD70944.
DR   GeneID; 3168712; -.
DR   KEGG; ttj:TTHA1121; -.
DR   PATRIC; fig|300852.9.peg.1100; -.
DR   eggNOG; COG0781; Bacteria.
DR   HOGENOM; CLU_087843_3_0_0; -.
DR   OMA; DRMPVVD; -.
DR   PhylomeDB; Q5SJ93; -.
DR   Proteomes; UP000000532; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.940.10; -; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   PANTHER; PTHR11078; PTHR11078; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; SSF48013; 1.
DR   TIGRFAMs; TIGR01951; nusB; 1.
PE   3: Inferred from homology;
KW   Reference proteome; RNA-binding; Transcription;
KW   Transcription antitermination; Transcription regulation.
FT   CHAIN           1..151
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000265618"
SQ   SEQUENCE   151 AA;  16958 MW;  FE41A27D941B8D3E CRC64;
     MRRRARELAM RALFAHTVGG MGLEEAFQHA LEEMGGEEEG YAEPLDQEGV AFARRLLSGY
     KAHQEEVDRV LEETVEGWDF RQMAKTDLAV LRLAVYEMLY EPTPFEPLIE VAVKIANRYG
     GEHSGSFVNG VLARVYRRVA AGELKTVAKE A