NUSB_VIBC3
ID NUSB_VIBC3 Reviewed; 156 AA.
AC A5F5Z6; C3M3M4;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN OrderedLocusNames=VC0395_A1857, VC395_2383;
OS Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS O395).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=345073;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA Heidelberg J.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA Wang W., Wang J., Qian W., Li D., Wang L.;
RT "A recalibrated molecular clock and independent origins for the cholera
RT pandemic clones.";
RL PLoS ONE 3:E4053-E4053(2008).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
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DR EMBL; CP000627; ABQ19650.1; -; Genomic_DNA.
DR EMBL; CP001235; ACP10373.1; -; Genomic_DNA.
DR RefSeq; WP_000501296.1; NZ_JAACZH010000008.1.
DR AlphaFoldDB; A5F5Z6; -.
DR SMR; A5F5Z6; -.
DR STRING; 345073.VC395_2383; -.
DR EnsemblBacteria; ABQ19650; ABQ19650; VC0395_A1857.
DR GeneID; 57740889; -.
DR GeneID; 66939884; -.
DR KEGG; vco:VC0395_A1857; -.
DR KEGG; vcr:VC395_2383; -.
DR PATRIC; fig|345073.21.peg.2297; -.
DR eggNOG; COG0781; Bacteria.
DR HOGENOM; CLU_087843_4_1_6; -.
DR OMA; DRMPVVD; -.
DR Proteomes; UP000000249; Chromosome 2.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; -; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR PANTHER; PTHR11078; PTHR11078; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; SSF48013; 1.
DR TIGRFAMs; TIGR01951; nusB; 1.
PE 3: Inferred from homology;
KW RNA-binding; Transcription; Transcription antitermination;
KW Transcription regulation.
FT CHAIN 1..156
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_1000071194"
SQ SEQUENCE 156 AA; 17675 MW; 01AF561DA46E4115 CRC64;
MGASVKPAAR RNARQFALQA IYSWQITKEN VATIEEQFLT SGKYDEEEHR AAEPALAAPE
TDVSYFRDLL AGVVLNHNEL DSKLRPFVSR PMQDLDMMEL ALLRLAMYEM TRREDVPYKV
VINEAIELAK VFAAEDSHKF VNGVLDKAAP HVRKKA