ID   NUSG_LACLA              Reviewed;         185 AA.
AC   Q9CDV7;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000255|HAMAP-Rule:MF_00948};
GN   Name=nusG {ECO:0000255|HAMAP-Rule:MF_00948}; OrderedLocusNames=LL2104;
GN   ORFNames=L157316;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- FUNCTION: Participates in transcription elongation, termination and
CC       antitermination. {ECO:0000255|HAMAP-Rule:MF_00948}.
CC   -!- SIMILARITY: Belongs to the NusG family. {ECO:0000255|HAMAP-
CC       Rule:MF_00948}.
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DR   EMBL; AE005176; AAK06202.1; -; Genomic_DNA.
DR   PIR; H86887; H86887.
DR   RefSeq; NP_268261.1; NC_002662.1.
DR   RefSeq; WP_003129977.1; NC_002662.1.
DR   AlphaFoldDB; Q9CDV7; -.
DR   SMR; Q9CDV7; -.
DR   STRING; 272623.L157316; -.
DR   PaxDb; Q9CDV7; -.
DR   EnsemblBacteria; AAK06202; AAK06202; L157316.
DR   GeneID; 60356849; -.
DR   GeneID; 66443098; -.
DR   KEGG; lla:L157316; -.
DR   PATRIC; fig|272623.7.peg.2263; -.
DR   eggNOG; COG0250; Bacteria.
DR   HOGENOM; CLU_067287_1_1_9; -.
DR   OMA; DGPFNGF; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 3.30.70.940; -; 1.
DR   HAMAP; MF_00948; NusG; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR006645; NGN_dom.
DR   InterPro; IPR036735; NGN_dom_sf.
DR   InterPro; IPR043425; NusG-like.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR   InterPro; IPR015869; Transcrpt_antiterm_NusG_bac_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR30265; PTHR30265; 1.
DR   PANTHER; PTHR30265:SF2; PTHR30265:SF2; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF02357; NusG; 1.
DR   PRINTS; PR00338; NUSGTNSCPFCT.
DR   SMART; SM00739; KOW; 1.
DR   SMART; SM00738; NGN; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   SUPFAM; SSF82679; SSF82679; 1.
DR   TIGRFAMs; TIGR00922; nusG; 1.
DR   PROSITE; PS01014; NUSG; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Transcription; Transcription antitermination;
KW   Transcription regulation; Transcription termination.
FT   CHAIN           1..185
FT                   /note="Transcription termination/antitermination protein
FT                   NusG"
FT                   /id="PRO_0000113932"
FT   DOMAIN          134..164
FT                   /note="KOW"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00948"
SQ   SEQUENCE   185 AA;  21110 MW;  A80C0B4E4D6AEF20 CRC64;
     MEDNNLVSFD QGWFVIQTYA GYERKVKEDL LERAELYNMA DKILRVEIPT ETIRTEVNGK
     MKEVEENLFP GYVLVEMNMT DEAWFIVRNT PNVTGFVGSH GNRSKPTPLF EQEIQDILVG
     MGKVVREIDF DVFVGKRVRI VDGAFSGFEA PITEINGDKL TLTVDMFGRA TPVELDMHQI
     EDIQA