ID   NUSG_MYCGE              Reviewed;         316 AA.
AC   P47300; Q49344;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000255|HAMAP-Rule:MF_00948};
GN   Name=nusG {ECO:0000255|HAMAP-Rule:MF_00948}; OrderedLocusNames=MG054;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 16-229 AND 240-316.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
CC   -!- FUNCTION: Participates in transcription elongation, termination and
CC       antitermination. {ECO:0000255|HAMAP-Rule:MF_00948}.
CC   -!- SIMILARITY: Belongs to the NusG family. {ECO:0000255|HAMAP-
CC       Rule:MF_00948}.
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DR   EMBL; L43967; AAC71270.1; -; Genomic_DNA.
DR   EMBL; U01710; AAB01022.1; -; Genomic_DNA.
DR   EMBL; U02236; AAA03388.1; -; Genomic_DNA.
DR   PIR; I64205; I64205.
DR   RefSeq; WP_009885716.1; NZ_AAGX01000003.1.
DR   AlphaFoldDB; P47300; -.
DR   STRING; 243273.MG_054; -.
DR   EnsemblBacteria; AAC71270; AAC71270; MG_054.
DR   KEGG; mge:MG_054; -.
DR   eggNOG; COG0250; Bacteria.
DR   HOGENOM; CLU_879462_0_0_14; -.
DR   OMA; IYSEDAW; -.
DR   OrthoDB; 2027986at2; -.
DR   BioCyc; MGEN243273:G1GJ2-55-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.940; -; 1.
DR   HAMAP; MF_00948; NusG; 1.
DR   InterPro; IPR006645; NGN_dom.
DR   InterPro; IPR036735; NGN_dom_sf.
DR   InterPro; IPR043425; NusG-like.
DR   InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR   InterPro; IPR010216; Transcrpt_antiterm_NusG_myco.
DR   PANTHER; PTHR30265; PTHR30265; 1.
DR   PANTHER; PTHR30265:SF2; PTHR30265:SF2; 1.
DR   Pfam; PF02357; NusG; 1.
DR   SMART; SM00738; NGN; 1.
DR   SUPFAM; SSF82679; SSF82679; 1.
DR   TIGRFAMs; TIGR01956; NusG_myco; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Transcription; Transcription antitermination;
KW   Transcription regulation; Transcription termination.
FT   CHAIN           1..316
FT                   /note="Transcription termination/antitermination protein
FT                   NusG"
FT                   /id="PRO_0000113974"
FT   CONFLICT        240..241
FT                   /note="FL -> LF (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   316 AA;  36323 MW;  852E1D8A7F5E22BB CRC64;
     MQASELTPKW YVAPVSIKDE AVVKNLKAKI QALGFNHEIV DVKVLKEREV HEEVYSLKSG
     KLPRSLKNTT FNKWFVLDDY RYLRVKISEK NLLGRYIYIK MIYSEDAWRI VRNFPGITGI
     VGSSGRGALP IPLDEKDANN LEQMLKGISI NPSKRIMLTN TAIIEMDSDK FDEKFQYILK
     QKQAIQKPKE DEDSEIVDAE KLKEAFKKLQ NSQEQDEWKE KATIIQSEQT KLDPSVLVPF
     LGKYEILDTD NKVEQLFEFS VGNLVEVHLT DTIHVQGQIK ALYQGTVNKA VVEIELTSKT
     QLINLPLENL SFVEFE