ID   NUSG_MYCTO              Reviewed;         238 AA.
AC   P9WIU8; L0T7B3; P65589; P96930;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000255|HAMAP-Rule:MF_00948};
GN   Name=nusG {ECO:0000255|HAMAP-Rule:MF_00948}; OrderedLocusNames=MT0668;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Participates in transcription elongation, termination and
CC       antitermination. {ECO:0000255|HAMAP-Rule:MF_00948}.
CC   -!- SIMILARITY: Belongs to the NusG family. {ECO:0000255|HAMAP-
CC       Rule:MF_00948}.
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DR   EMBL; AE000516; AAK44893.1; -; Genomic_DNA.
DR   PIR; D70613; D70613.
DR   RefSeq; WP_003403288.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WIU8; -.
DR   BMRB; P9WIU8; -.
DR   SMR; P9WIU8; -.
DR   EnsemblBacteria; AAK44893; AAK44893; MT0668.
DR   GeneID; 45424599; -.
DR   KEGG; mtc:MT0668; -.
DR   PATRIC; fig|83331.31.peg.710; -.
DR   HOGENOM; CLU_067287_0_2_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 3.30.70.940; -; 1.
DR   HAMAP; MF_00948; NusG; 1.
DR   InterPro; IPR006645; NGN_dom.
DR   InterPro; IPR036735; NGN_dom_sf.
DR   InterPro; IPR043425; NusG-like.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR   InterPro; IPR015869; Transcrpt_antiterm_NusG_bac_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR30265; PTHR30265; 1.
DR   PANTHER; PTHR30265:SF2; PTHR30265:SF2; 1.
DR   Pfam; PF02357; NusG; 1.
DR   PRINTS; PR00338; NUSGTNSCPFCT.
DR   SMART; SM00738; NGN; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   SUPFAM; SSF82679; SSF82679; 1.
DR   TIGRFAMs; TIGR00922; nusG; 1.
DR   PROSITE; PS01014; NUSG; 1.
PE   3: Inferred from homology;
KW   Transcription; Transcription antitermination; Transcription regulation;
KW   Transcription termination.
FT   CHAIN           1..238
FT                   /note="Transcription termination/antitermination protein
FT                   NusG"
FT                   /id="PRO_0000427942"
SQ   SEQUENCE   238 AA;  25447 MW;  E083F9754E42144C CRC64;
     MTTFDGDTSA GEAVDLTEAN AFQDAAAPAE EVDPAAALKA ELRSKPGDWY VVHSYAGYEN
     KVKANLETRV QNLDVGDYIF QVEVPTEEVT EIKNGQRKQV NRKVLPGYIL VRMDLTDDSW
     AAVRNTPGVT GFVGATSRPS ALALDDVVKF LLPRGSTRKA AKGAASTAAA AEAGGLERPV
     VEVDYEVGES VTVMDGPFAT LPATISEVNA EQQKLKVLVS IFGRETPVEL TFGQVSKI