NUSG_STAAM
ID NUSG_STAAM Reviewed; 182 AA.
AC P0A095; O08386;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000255|HAMAP-Rule:MF_00948};
GN Name=nusG {ECO:0000255|HAMAP-Rule:MF_00948}; OrderedLocusNames=SAV0535;
OS Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=158878;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mu50 / ATCC 700699;
RX PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA Hiramatsu K.;
RT "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL Lancet 357:1225-1240(2001).
CC -!- FUNCTION: Participates in transcription elongation, termination and
CC antitermination. {ECO:0000255|HAMAP-Rule:MF_00948}.
CC -!- SIMILARITY: Belongs to the NusG family. {ECO:0000255|HAMAP-
CC Rule:MF_00948}.
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DR EMBL; BA000017; BAB56697.1; -; Genomic_DNA.
DR RefSeq; WP_001288302.1; NC_002758.2.
DR AlphaFoldDB; P0A095; -.
DR SMR; P0A095; -.
DR World-2DPAGE; 0002:P0A095; -.
DR PaxDb; P0A095; -.
DR EnsemblBacteria; BAB56697; BAB56697; SAV0535.
DR KEGG; sav:SAV0535; -.
DR HOGENOM; CLU_067287_1_1_9; -.
DR OMA; DGPFNGF; -.
DR PhylomeDB; P0A095; -.
DR BioCyc; SAUR158878:SAV_RS03005-MON; -.
DR Proteomes; UP000002481; Chromosome.
DR GO; GO:0006354; P:DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 3.30.70.940; -; 1.
DR HAMAP; MF_00948; NusG; 1.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR006645; NGN_dom.
DR InterPro; IPR036735; NGN_dom_sf.
DR InterPro; IPR043425; NusG-like.
DR InterPro; IPR014722; Rib_L2_dom2.
DR InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR InterPro; IPR015869; Transcrpt_antiterm_NusG_bac_CS.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR30265; PTHR30265; 1.
DR PANTHER; PTHR30265:SF2; PTHR30265:SF2; 1.
DR Pfam; PF00467; KOW; 1.
DR Pfam; PF02357; NusG; 1.
DR PRINTS; PR00338; NUSGTNSCPFCT.
DR SMART; SM00739; KOW; 1.
DR SMART; SM00738; NGN; 1.
DR SUPFAM; SSF50104; SSF50104; 1.
DR SUPFAM; SSF82679; SSF82679; 1.
DR TIGRFAMs; TIGR00922; nusG; 1.
DR PROSITE; PS01014; NUSG; 1.
PE 3: Inferred from homology;
KW Transcription; Transcription antitermination; Transcription regulation;
KW Transcription termination.
FT CHAIN 1..182
FT /note="Transcription termination/antitermination protein
FT NusG"
FT /id="PRO_0000113948"
FT DOMAIN 131..163
FT /note="KOW"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00948"
SQ SEQUENCE 182 AA; 20664 MW; 879D32CEC10DC869 CRC64;
MSEEVGAKRW YAVHTYSGYE NKVKKNLEKR VESMNMTEQI FRVVIPEEEE TQVKDGKAKT
TVKKTFPGYV LVELIMTDES WYVVRNTPGV TGFVGSAGAG SKPNPLLPEE VRFILKQMGL
KEKTIDVELE VGEQVRIKSG PFANQVGEVQ EIETDKFKLT VLVDMFGRET PVEVEFDQIE
KL