ID   NUSG_STAES              Reviewed;         182 AA.
AC   Q8CQ85;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000255|HAMAP-Rule:MF_00948};
GN   Name=nusG {ECO:0000255|HAMAP-Rule:MF_00948}; OrderedLocusNames=SE_0299;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- FUNCTION: Participates in transcription elongation, termination and
CC       antitermination. {ECO:0000255|HAMAP-Rule:MF_00948}.
CC   -!- SIMILARITY: Belongs to the NusG family. {ECO:0000255|HAMAP-
CC       Rule:MF_00948}.
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DR   EMBL; AE015929; AAO03896.1; -; Genomic_DNA.
DR   RefSeq; NP_763854.1; NC_004461.1.
DR   RefSeq; WP_001832303.1; NZ_WBME01000014.1.
DR   AlphaFoldDB; Q8CQ85; -.
DR   SMR; Q8CQ85; -.
DR   STRING; 176280.SE_0299; -.
DR   EnsemblBacteria; AAO03896; AAO03896; SE_0299.
DR   GeneID; 50019535; -.
DR   KEGG; sep:SE_0299; -.
DR   PATRIC; fig|176280.10.peg.275; -.
DR   eggNOG; COG0250; Bacteria.
DR   HOGENOM; CLU_067287_1_1_9; -.
DR   OMA; DGPFNGF; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 3.30.70.940; -; 1.
DR   HAMAP; MF_00948; NusG; 1.
DR   InterPro; IPR006645; NGN_dom.
DR   InterPro; IPR036735; NGN_dom_sf.
DR   InterPro; IPR043425; NusG-like.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR   InterPro; IPR015869; Transcrpt_antiterm_NusG_bac_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR30265; PTHR30265; 1.
DR   PANTHER; PTHR30265:SF2; PTHR30265:SF2; 1.
DR   Pfam; PF02357; NusG; 1.
DR   PRINTS; PR00338; NUSGTNSCPFCT.
DR   SMART; SM00738; NGN; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   SUPFAM; SSF82679; SSF82679; 1.
DR   TIGRFAMs; TIGR00922; nusG; 1.
DR   PROSITE; PS01014; NUSG; 1.
PE   3: Inferred from homology;
KW   Transcription; Transcription antitermination; Transcription regulation;
KW   Transcription termination.
FT   CHAIN           1..182
FT                   /note="Transcription termination/antitermination protein
FT                   NusG"
FT                   /id="PRO_0000113954"
FT   DOMAIN          131..163
FT                   /note="KOW"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00948"
SQ   SEQUENCE   182 AA;  20673 MW;  D403BF46C51E9E5F CRC64;
     MSEEVGAKRW YAVHTYSGYE NKVKKNLEKR VESMNMTEQI FRVVIPEEEE TQVKDGKAKK
     LVKKTFPGYV LVELIMTDES WYVVRNTPGV TGFVGSAGAG SKPNPLLPEE VRFILKQMGL
     KEKTIDVELD VGEQVRIQSG PFANQIGEVQ EIEADKFKLT VLVDMFGRET PVEVEFDQIE
     KL