ID   NUSG_SYNY3              Reviewed;         205 AA.
AC   P36265;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 126.
DE   RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000255|HAMAP-Rule:MF_00948};
GN   Name=nusG {ECO:0000255|HAMAP-Rule:MF_00948}; OrderedLocusNames=sll1742;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7685084; DOI=10.1093/nar/21.10.2519;
RA   Schmidt J., Subramanian A.R.;
RT   "Sequence of the cyanobacterial tRNA(w) gene in Synechocystis PCC 6803:
RT   requirement of enzymatic 3' CCA attachment to the acceptor stem.";
RL   Nucleic Acids Res. 21:2519-2519(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 177-205.
RX   PubMed=7505271; DOI=10.1016/s0021-9258(19)74268-9;
RA   Schmidt J., Bubunenko M., Subramanian A.R.;
RT   "A novel operon organization involving the genes for chorismate synthase
RT   (aromatic biosynthesis pathway) and ribosomal GTPase center proteins (L11,
RT   L1, L10, L12: rplKAJL) in cyanobacterium Synechocystis PCC 6803.";
RL   J. Biol. Chem. 268:27447-27457(1993).
CC   -!- FUNCTION: Participates in transcription elongation, termination and
CC       antitermination. {ECO:0000255|HAMAP-Rule:MF_00948}.
CC   -!- SIMILARITY: Belongs to the NusG family. {ECO:0000255|HAMAP-
CC       Rule:MF_00948}.
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DR   EMBL; X72627; CAA51202.1; -; Genomic_DNA.
DR   EMBL; BA000022; BAA17420.1; -; Genomic_DNA.
DR   EMBL; X73005; CAA51490.1; -; Genomic_DNA.
DR   PIR; S33696; E49316.
DR   AlphaFoldDB; P36265; -.
DR   SMR; P36265; -.
DR   IntAct; P36265; 2.
DR   STRING; 1148.1652499; -.
DR   PaxDb; P36265; -.
DR   EnsemblBacteria; BAA17420; BAA17420; BAA17420.
DR   KEGG; syn:sll1742; -.
DR   eggNOG; COG0250; Bacteria.
DR   InParanoid; P36265; -.
DR   OMA; DGPFNGF; -.
DR   PhylomeDB; P36265; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 3.30.70.940; -; 1.
DR   HAMAP; MF_00948; NusG; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR006645; NGN_dom.
DR   InterPro; IPR036735; NGN_dom_sf.
DR   InterPro; IPR043425; NusG-like.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR   InterPro; IPR015869; Transcrpt_antiterm_NusG_bac_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR30265; PTHR30265; 1.
DR   PANTHER; PTHR30265:SF2; PTHR30265:SF2; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF02357; NusG; 1.
DR   PRINTS; PR00338; NUSGTNSCPFCT.
DR   SMART; SM00739; KOW; 1.
DR   SMART; SM00738; NGN; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   SUPFAM; SSF82679; SSF82679; 1.
DR   TIGRFAMs; TIGR00922; nusG; 1.
DR   PROSITE; PS01014; NUSG; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Transcription; Transcription antitermination;
KW   Transcription regulation; Transcription termination.
FT   CHAIN           1..205
FT                   /note="Transcription termination/antitermination protein
FT                   NusG"
FT                   /id="PRO_0000113964"
FT   DOMAIN          154..178
FT                   /note="KOW"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00948"
SQ   SEQUENCE   205 AA;  23416 MW;  26D4E75485534FF6 CRC64;
     MSFTDDQSPV AEQNKKTPSE GHWFAVQVAS GCEKRVKLNL EQRIHTLDVA DRILQVEIPK
     TPIVKIRKDG ARVQGEEKIF PGYVLIRMIM DDDAWQVVKN TPHVINFVGS EQKRHYGRGR
     GHVLPMPLSH GEVERIFRHV DEQEPVVKID MEIGDHIMVL SGPFKDFEGD VIEVSPERSK
     LKALLSIFGR ETPVELEFTQ VEKQN