NUSG_TREPA
ID NUSG_TREPA Reviewed; 185 AA.
AC O83264;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000255|HAMAP-Rule:MF_00948};
GN Name=nusG {ECO:0000255|HAMAP-Rule:MF_00948}; OrderedLocusNames=TP_0236;
OS Treponema pallidum (strain Nichols).
OC Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX NCBI_TaxID=243276;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nichols;
RX PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA Venter J.C.;
RT "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL Science 281:375-388(1998).
CC -!- FUNCTION: Participates in transcription elongation, termination and
CC antitermination. {ECO:0000255|HAMAP-Rule:MF_00948}.
CC -!- SIMILARITY: Belongs to the NusG family. {ECO:0000255|HAMAP-
CC Rule:MF_00948}.
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DR EMBL; AE000520; AAC65224.1; -; Genomic_DNA.
DR PIR; F71349; F71349.
DR RefSeq; WP_010881684.1; NC_021490.2.
DR AlphaFoldDB; O83264; -.
DR SMR; O83264; -.
DR IntAct; O83264; 6.
DR STRING; 243276.TPANIC_0236; -.
DR PRIDE; O83264; -.
DR EnsemblBacteria; AAC65224; AAC65224; TP_0236.
DR GeneID; 57878778; -.
DR KEGG; tpa:TP_0236; -.
DR eggNOG; COG0250; Bacteria.
DR HOGENOM; CLU_067287_1_0_12; -.
DR OMA; DGPFNGF; -.
DR OrthoDB; 2027986at2; -.
DR Proteomes; UP000000811; Chromosome.
DR GO; GO:0006354; P:DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 3.30.70.940; -; 1.
DR HAMAP; MF_00948; NusG; 1.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR006645; NGN_dom.
DR InterPro; IPR036735; NGN_dom_sf.
DR InterPro; IPR043425; NusG-like.
DR InterPro; IPR014722; Rib_L2_dom2.
DR InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR InterPro; IPR015869; Transcrpt_antiterm_NusG_bac_CS.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR30265; PTHR30265; 1.
DR PANTHER; PTHR30265:SF2; PTHR30265:SF2; 1.
DR Pfam; PF00467; KOW; 1.
DR Pfam; PF02357; NusG; 1.
DR PRINTS; PR00338; NUSGTNSCPFCT.
DR SMART; SM00739; KOW; 1.
DR SMART; SM00738; NGN; 1.
DR SUPFAM; SSF50104; SSF50104; 1.
DR SUPFAM; SSF82679; SSF82679; 1.
DR TIGRFAMs; TIGR00922; nusG; 1.
DR PROSITE; PS01014; NUSG; 1.
PE 3: Inferred from homology;
KW Reference proteome; Transcription; Transcription antitermination;
KW Transcription regulation; Transcription termination.
FT CHAIN 1..185
FT /note="Transcription termination/antitermination protein
FT NusG"
FT /id="PRO_0000113967"
FT DOMAIN 134..163
FT /note="KOW"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00948"
SQ SEQUENCE 185 AA; 20928 MW; DF9DB89A4A2F9F52 CRC64;
MAKEWYILHT FSGREARVER AVRMLVEHAR IPTNVIFDIK IPEELLTEVK DGKKRVVRRK
FFPGYLLVEM DLPEVDWRIV CNEVRRIPGV SGFLGSSGNA KPQAVSADEA RRILQKAGEI
KGDRTPRIAQ TFLVGQQVRI VEGPFATFSG EVEEVMSERN KVRVAVTIFG RATPVELELV
QVEAL
