NUSG_VIBCH
ID NUSG_VIBCH Reviewed; 182 AA.
AC Q9KV35;
DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000255|HAMAP-Rule:MF_00948};
GN Name=nusG {ECO:0000255|HAMAP-Rule:MF_00948}; OrderedLocusNames=VC_0323;
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- FUNCTION: Participates in transcription elongation, termination and
CC antitermination. {ECO:0000255|HAMAP-Rule:MF_00948}.
CC -!- SIMILARITY: Belongs to the NusG family. {ECO:0000255|HAMAP-
CC Rule:MF_00948}.
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DR EMBL; AE003852; AAF93496.1; -; Genomic_DNA.
DR PIR; A82338; A82338.
DR RefSeq; NP_229977.1; NC_002505.1.
DR RefSeq; WP_001287510.1; NZ_LT906614.1.
DR AlphaFoldDB; Q9KV35; -.
DR SMR; Q9KV35; -.
DR STRING; 243277.VC_0323; -.
DR DNASU; 2615089; -.
DR EnsemblBacteria; AAF93496; AAF93496; VC_0323.
DR GeneID; 57991494; -.
DR KEGG; vch:VC_0323; -.
DR PATRIC; fig|243277.26.peg.300; -.
DR eggNOG; COG0250; Bacteria.
DR HOGENOM; CLU_067287_1_0_6; -.
DR OMA; DGPFNGF; -.
DR BioCyc; VCHO:VC0323-MON; -.
DR Proteomes; UP000000584; Chromosome 1.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0006354; P:DNA-templated transcription, elongation; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-UniRule.
DR GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 3.30.70.940; -; 1.
DR HAMAP; MF_00948; NusG; 1.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR006645; NGN_dom.
DR InterPro; IPR036735; NGN_dom_sf.
DR InterPro; IPR043425; NusG-like.
DR InterPro; IPR014722; Rib_L2_dom2.
DR InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR InterPro; IPR015869; Transcrpt_antiterm_NusG_bac_CS.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR30265; PTHR30265; 1.
DR PANTHER; PTHR30265:SF2; PTHR30265:SF2; 1.
DR Pfam; PF00467; KOW; 1.
DR Pfam; PF02357; NusG; 1.
DR PRINTS; PR00338; NUSGTNSCPFCT.
DR SMART; SM00739; KOW; 1.
DR SMART; SM00738; NGN; 1.
DR SUPFAM; SSF50104; SSF50104; 1.
DR SUPFAM; SSF82679; SSF82679; 1.
DR TIGRFAMs; TIGR00922; nusG; 1.
DR PROSITE; PS01014; NUSG; 1.
PE 3: Inferred from homology;
KW Reference proteome; Transcription; Transcription antitermination;
KW Transcription regulation; Transcription termination.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..182
FT /note="Transcription termination/antitermination protein
FT NusG"
FT /id="PRO_0000113968"
FT DOMAIN 131..161
FT /note="KOW"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00948"
SQ SEQUENCE 182 AA; 20651 MW; 7ED74AE5B504F612 CRC64;
MSEAPKKRWY VVQAFSGFEG RVAQSLREHI KMHGMEELFG EVLVPTEEVV EMRAGQRRKS
ERKFFPGYVL VQMIMNDESW HLVRSVPRVM GFIGGTSDRP APITDKEADA ILNRLEKASE
APRPKTMFEA GEVVRVNDGP FADFNGTVEE VDYEKSRLKV SVSIFGRATP VELEFGQVEK
LD