ID   NV6_NEMVE               Reviewed;          85 AA.
AC   P0DQR2;
DT   29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT   29-SEP-2021, sequence version 1.
DT   03-AUG-2022, entry version 3.
DE   RecName: Full=N.vectensis toxin 6 {ECO:0000305};
DE            Short=Nv6 {ECO:0000303|PubMed:31134275};
DE   Flags: Precursor;
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=31134275; DOI=10.1093/molbev/msz132;
RA   Sachkova M.Y., Singer S.A., Macrander J., Reitzel A.M., Peigneur S.,
RA   Tytgat J., Moran Y.;
RT   "The birth and death of toxins with distinct functions: a case study in the
RT   sea anemone Nematostella.";
RL   Mol. Biol. Evol. 36:2001-2012(2019).
CC   -!- FUNCTION: Probable toxin. {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: No protein detected at any developmental stage,
CC       probably due to low expression levels (PubMed:31134275). At
CC       transcriptional level, is found in the larval stage (PubMed:31134275).
CC       {ECO:0000269|PubMed:31134275}.
CC   -!- WEB RESOURCE: Name=National Center for Biotechnology Information
CC       (NCBI);
CC       URL="https://www.ncbi.nlm.nih.gov/nucleotide/XR_004295222.1?report=genbank&log$=nucltop&blast_rank=1&RID=CTDBJRB3013";
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DR   SMR; P0DQR2; -.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.20.20.10; -; 1.
DR   InterPro; IPR023355; Myo_ane_neurotoxin_sf.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Signal; Toxin.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..85
FT                   /note="N.vectensis toxin 6"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000453817"
FT   DISULFID        46..82
FT                   /evidence="ECO:0000250|UniProtKB:P19651"
FT   DISULFID        48..71
FT                   /evidence="ECO:0000250|UniProtKB:P19651"
FT   DISULFID        64..83
FT                   /evidence="ECO:0000250|UniProtKB:P19651"
SQ   SEQUENCE   85 AA;  9541 MW;  13AB02D5D5499D2F CRC64;
     MISFKTVIVC LFLWVVIIGA RHRPVKLDDE IFRDYHIDID PSKSSCRCDD DGAEGSGTVW
     YGNCPSGWAM CTSSHYSAFA ECCKQ