NV7_NEMVE
ID NV7_NEMVE Reviewed; 89 AA.
AC P0DQR3;
DT 29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT 29-SEP-2021, sequence version 1.
DT 23-FEB-2022, entry version 2.
DE RecName: Full=N.vectensis toxin 7 {ECO:0000305};
DE Short=Nv7 {ECO:0000303|PubMed:31134275};
DE Flags: Precursor;
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION BY MASS SPECTROMETRY, TISSUE
RP SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=31134275; DOI=10.1093/molbev/msz132;
RA Sachkova M.Y., Singer S.A., Macrander J., Reitzel A.M., Peigneur S.,
RA Tytgat J., Moran Y.;
RT "The birth and death of toxins with distinct functions: a case study in the
RT sea anemone Nematostella.";
RL Mol. Biol. Evol. 36:2001-2012(2019).
CC -!- FUNCTION: Probable toxin. {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in ectodermal gland cells.
CC {ECO:0000305|PubMed:31134275}.
CC -!- DEVELOPMENTAL STAGE: Is detected in unfertilized eggs, late planulae,
CC primary polyps and adult females (but not males) (at protein level).
CC {ECO:0000269|PubMed:31134275}.
CC -!- WEB RESOURCE: Name=National Center for Biotechnology Information
CC (NCBI);
CC URL="https://www.ncbi.nlm.nih.gov/nucleotide/XR_004295599.1?report=genbank&log$=nucltop&blast_rank=1&RID=CTDFKA6D013";
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DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Disulfide bond; Signal; Toxin.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..89
FT /note="N.vectensis toxin 7"
FT /evidence="ECO:0000305"
FT /id="PRO_0000453818"
FT DISULFID 44..77
FT /evidence="ECO:0000250|UniProtKB:P19651"
FT DISULFID 46..69
FT /evidence="ECO:0000250|UniProtKB:P19651"
FT DISULFID 62..78
FT /evidence="ECO:0000250|UniProtKB:P19651"
SQ SEQUENCE 89 AA; 9459 MW; 3B960416570446C8 CRC64;
MASFFKIAVI CLVMLVVCSN ARVIDVDDDY LMDFAASKRG GQTCYCRGGS GPTGGFWGGQ
NCPAGMTSCR KNILGNCCQK SKEGTDCDI