ID   NXT1_SCHPO              Reviewed;         115 AA.
AC   P0CAN8; Q9HDY6;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=NTF2-related export protein 1;
DE   AltName: Full=p15;
GN   Name=nxt1; ORFNames=SPAPB1A10.03;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   REVISION OF GENE MODEL.
RG   Schizosaccharomyces pombe GeneDB;
RL   Unpublished observations (SEP-2008).
RN   [3]
RP   FUNCTION.
RX   PubMed=14963046; DOI=10.1074/jbc.m309731200;
RA   Thakurta A.G., Gopal G., Yoon J.H., Saha T., Dhar R.;
RT   "Conserved nuclear export sequences in Schizosaccharomyces pombe Mex67 and
RT   human TAP function in mRNA export by direct nuclear pore interactions.";
RL   J. Biol. Chem. 279:17434-17442(2004).
CC   -!- FUNCTION: Stimulator of protein export for NES-containing proteins (By
CC       similarity). Also plays a role in mRNA nuclear export. {ECO:0000250,
CC       ECO:0000269|PubMed:14963046}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CU329670; CAC21476.2; -; Genomic_DNA.
DR   RefSeq; NP_593517.2; NM_001018951.2.
DR   AlphaFoldDB; P0CAN8; -.
DR   SMR; P0CAN8; -.
DR   BioGRID; 280058; 20.
DR   STRING; 4896.SPAPB1A10.03.1; -.
DR   PaxDb; P0CAN8; -.
DR   EnsemblFungi; SPAPB1A10.03.1; SPAPB1A10.03.1:pep; SPAPB1A10.03.
DR   GeneID; 2543644; -.
DR   KEGG; spo:SPAPB1A10.03; -.
DR   PomBase; SPAPB1A10.03; nxt1.
DR   VEuPathDB; FungiDB:SPAPB1A10.03; -.
DR   eggNOG; KOG4353; Eukaryota.
DR   HOGENOM; CLU_2110387_0_0_1; -.
DR   InParanoid; P0CAN8; -.
DR   OMA; MGNDMNI; -.
DR   Reactome; R-SPO-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript.
DR   PRO; PR:P0CAN8; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0044613; C:nuclear pore central transport channel; IBA:GO_Central.
DR   GO; GO:0042272; C:nuclear RNA export factor complex; IPI:PomBase.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IBA:GO_Central.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IPI:PomBase.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   GO; GO:0000054; P:ribosomal subunit export from nucleus; ISO:PomBase.
DR   CDD; cd00780; NTF2; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR045875; NTF2/Mtr2.
DR   InterPro; IPR002075; NTF2_dom.
DR   InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR   PANTHER; PTHR12612; PTHR12612; 1.
DR   Pfam; PF02136; NTF2; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
DR   PROSITE; PS50177; NTF2_DOMAIN; 1.
PE   3: Inferred from homology;
KW   mRNA transport; Nucleus; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..115
FT                   /note="NTF2-related export protein 1"
FT                   /id="PRO_0000373860"
FT   DOMAIN          7..115
FT                   /note="NTF2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00137"
SQ   SEQUENCE   115 AA;  13395 MW;  925300E29819C885 CRC64;
     MESSVKYAQE FVQRYYSSLD TNRNGIAEFY RENSLILWNG KPMQVTEFTS MIVNLPYSKT
     KVEDFDSQQV MGNDMNIIIV VSGTIRFDGK KPHVFSYVSF YCIYLLVLRS STNFL