ID   NXT2_BOVIN              Reviewed;         142 AA.
AC   A6QNX3;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=NTF2-related export protein 2;
GN   Name=NXT2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Brain cortex;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulator of protein export for NES-containing proteins. Also
CC       plays a role in mRNA nuclear export (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with NXF1, NXF2, NXF3 and NXF5. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
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DR   EMBL; BC149046; AAI49047.1; -; mRNA.
DR   RefSeq; NP_001093823.1; NM_001100353.1.
DR   RefSeq; XP_005227925.1; XM_005227868.3.
DR   RefSeq; XP_005227926.1; XM_005227869.3.
DR   AlphaFoldDB; A6QNX3; -.
DR   SMR; A6QNX3; -.
DR   STRING; 9913.ENSBTAP00000027635; -.
DR   PaxDb; A6QNX3; -.
DR   PRIDE; A6QNX3; -.
DR   Ensembl; ENSBTAT00000027635; ENSBTAP00000027635; ENSBTAG00000020739.
DR   Ensembl; ENSBTAT00000074580; ENSBTAP00000060869; ENSBTAG00000020739.
DR   Ensembl; ENSBTAT00000075164; ENSBTAP00000060652; ENSBTAG00000020739.
DR   GeneID; 513043; -.
DR   KEGG; bta:513043; -.
DR   CTD; 55916; -.
DR   VEuPathDB; HostDB:ENSBTAG00000020739; -.
DR   VGNC; VGNC:32385; NXT2.
DR   eggNOG; KOG4353; Eukaryota.
DR   GeneTree; ENSGT00940000156381; -.
DR   HOGENOM; CLU_122448_1_1_1; -.
DR   InParanoid; A6QNX3; -.
DR   OMA; DHFTRLY; -.
DR   OrthoDB; 1450028at2759; -.
DR   TreeFam; TF318944; -.
DR   Proteomes; UP000009136; Chromosome X.
DR   Bgee; ENSBTAG00000020739; Expressed in corpus epididymis and 106 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0044613; C:nuclear pore central transport channel; IBA:GO_Central.
DR   GO; GO:0042272; C:nuclear RNA export factor complex; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IBA:GO_Central.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   CDD; cd00780; NTF2; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR045875; NTF2/Mtr2.
DR   InterPro; IPR002075; NTF2_dom.
DR   InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR   PANTHER; PTHR12612; PTHR12612; 1.
DR   Pfam; PF02136; NTF2; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
DR   PROSITE; PS50177; NTF2_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; mRNA transport; Nucleus; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..142
FT                   /note="NTF2-related export protein 2"
FT                   /id="PRO_0000378199"
FT   DOMAIN          17..136
FT                   /note="NTF2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00137"
SQ   SEQUENCE   142 AA;  16313 MW;  425EA4EB414CCBBE CRC64;
     MAMAVEFKTY VDQACRAAEE FVNIYYETMD KRRRALTRLY LDKATLIWNG NVVTGLEALA
     NFFDMLPSSE FQVNMLDCQP VHEQATQSQT TVLVVTSGTV KFDGNKQHYF NQNFLLTAQT
     TANNTVWKIA SDCFRFQDWA TI