ID   NXT2_CHICK              Reviewed;         141 AA.
AC   Q5ZLH0;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=NTF2-related export protein 2;
GN   Name=NXT2; ORFNames=RCJMB04_6d20;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Regulator of protein export for NES-containing proteins. Also
CC       plays a role in mRNA nuclear export (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with NXF1, NXF2, NXF3 and NXF5. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ719764; CAG31423.1; -; mRNA.
DR   RefSeq; NP_001006436.1; NM_001006436.1.
DR   RefSeq; XP_015133780.1; XM_015278294.1.
DR   AlphaFoldDB; Q5ZLH0; -.
DR   SMR; Q5ZLH0; -.
DR   STRING; 9031.ENSGALP00000013119; -.
DR   PaxDb; Q5ZLH0; -.
DR   Ensembl; ENSGALT00000013134; ENSGALP00000013119; ENSGALG00000008092.
DR   GeneID; 422346; -.
DR   KEGG; gga:422346; -.
DR   CTD; 55916; -.
DR   VEuPathDB; HostDB:geneid_422346; -.
DR   eggNOG; KOG4353; Eukaryota.
DR   GeneTree; ENSGT00940000156381; -.
DR   HOGENOM; CLU_122448_1_1_1; -.
DR   InParanoid; Q5ZLH0; -.
DR   OMA; DHFTRLY; -.
DR   OrthoDB; 1450028at2759; -.
DR   PhylomeDB; Q5ZLH0; -.
DR   Reactome; R-GGA-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript.
DR   PRO; PR:Q5ZLH0; -.
DR   Proteomes; UP000000539; Chromosome 4.
DR   Bgee; ENSGALG00000008092; Expressed in spermatid and 13 other tissues.
DR   ExpressionAtlas; Q5ZLH0; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0044613; C:nuclear pore central transport channel; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IBA:GO_Central.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   CDD; cd00780; NTF2; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR045875; NTF2/Mtr2.
DR   InterPro; IPR002075; NTF2_dom.
DR   InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR   PANTHER; PTHR12612; PTHR12612; 1.
DR   Pfam; PF02136; NTF2; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
DR   PROSITE; PS50177; NTF2_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; mRNA transport; Nucleus; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..141
FT                   /note="NTF2-related export protein 2"
FT                   /id="PRO_0000378202"
FT   DOMAIN          17..136
FT                   /note="NTF2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00137"
SQ   SEQUENCE   141 AA;  16162 MW;  26DD94D76A7F6980 CRC64;
     MAASVDFKTY VDQACRAAEE FVNIYYETMD KRRRALTRLY LDKATLIWNG NAVSGQEALN
     EFFEMLPSSE FQVNVLDCQP VHEQATQSQT TVLVVTCGTV KFDGNKQRYF NQNFLLTAQA
     TSNSTVWKIA SDCFRFQDWA N