ID   NXT2_RAT                Reviewed;         142 AA.
AC   B2GV77;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=NTF2-related export protein 2;
GN   Name=Nxt2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway;
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Regulator of protein export for NES-containing proteins. Also
CC       plays a role in mRNA nuclear export (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with NXF1, NXF2, NXF3 and NXF5. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
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DR   EMBL; CH474047; EDL85211.1; -; Genomic_DNA.
DR   EMBL; BC166561; AAI66561.1; -; mRNA.
DR   RefSeq; NP_001101590.1; NM_001108120.1.
DR   AlphaFoldDB; B2GV77; -.
DR   SMR; B2GV77; -.
DR   STRING; 10116.ENSRNOP00000025912; -.
DR   PhosphoSitePlus; B2GV77; -.
DR   PaxDb; B2GV77; -.
DR   PeptideAtlas; B2GV77; -.
DR   GeneID; 315352; -.
DR   KEGG; rno:315352; -.
DR   CTD; 55916; -.
DR   RGD; 1560204; Nxt2.
DR   eggNOG; KOG4353; Eukaryota.
DR   HOGENOM; CLU_122448_1_0_1; -.
DR   InParanoid; B2GV77; -.
DR   OrthoDB; 1450028at2759; -.
DR   PhylomeDB; B2GV77; -.
DR   PRO; PR:B2GV77; -.
DR   Proteomes; UP000002494; Unplaced.
DR   Proteomes; UP000234681; Chromosome x.
DR   Genevisible; B2GV77; RN.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0044613; C:nuclear pore central transport channel; IBA:GO_Central.
DR   GO; GO:0042272; C:nuclear RNA export factor complex; ISO:RGD.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IBA:GO_Central.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   CDD; cd00780; NTF2; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR045875; NTF2/Mtr2.
DR   InterPro; IPR002075; NTF2_dom.
DR   InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR   PANTHER; PTHR12612; PTHR12612; 1.
DR   Pfam; PF02136; NTF2; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
DR   PROSITE; PS50177; NTF2_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; mRNA transport; Nucleus; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..142
FT                   /note="NTF2-related export protein 2"
FT                   /id="PRO_0000378201"
FT   DOMAIN          17..136
FT                   /note="NTF2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00137"
SQ   SEQUENCE   142 AA;  16366 MW;  98981CCDCD1BF11F CRC64;
     MAMAVDFKMY VDQACRAAEE FVNIYYETMD KRRHALVRLY LDKATLIWNG NVVTGLEALA
     NFFEMLPSSE FQINMLDCQP VHEQATQYQT TVLVVTSGVV KFDGNKQHFF NQNFLLTAQS
     TPNSTVWKIA SDCFRFQDWA SI