O1009_MOUSE
ID O1009_MOUSE Reviewed; 314 AA.
AC Q8VFK1;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Olfactory receptor 1009;
DE AltName: Full=Olfactory receptor 175-3;
GN Name=Olfr1009; Synonyms=Mor175-3;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY073525; AAL61188.1; -; Genomic_DNA.
DR EMBL; AY318204; AAP71461.1; -; Genomic_DNA.
DR CCDS; CCDS16216.1; -.
DR RefSeq; NP_666783.1; NM_146572.2.
DR AlphaFoldDB; Q8VFK1; -.
DR SMR; Q8VFK1; -.
DR STRING; 10090.ENSMUSP00000061475; -.
DR GlyGen; Q8VFK1; 1 site.
DR PaxDb; Q8VFK1; -.
DR PRIDE; Q8VFK1; -.
DR DNASU; 258565; -.
DR Ensembl; ENSMUST00000055517; ENSMUSP00000061475; ENSMUSG00000043226.
DR Ensembl; ENSMUST00000216443; ENSMUSP00000150450; ENSMUSG00000043226.
DR GeneID; 258565; -.
DR KEGG; mmu:258565; -.
DR UCSC; uc008kkr.1; mouse.
DR CTD; 258565; -.
DR MGI; MGI:3030843; Olfr1009.
DR VEuPathDB; HostDB:ENSMUSG00000043226; -.
DR eggNOG; ENOG502RF13; Eukaryota.
DR GeneTree; ENSGT01050000244931; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q8VFK1; -.
DR OMA; HPRMQVF; -.
DR OrthoDB; 977912at2759; -.
DR PhylomeDB; Q8VFK1; -.
DR TreeFam; TF352753; -.
DR BioGRID-ORCS; 258565; 0 hits in 65 CRISPR screens.
DR PRO; PR:Q8VFK1; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q8VFK1; protein.
DR ExpressionAtlas; Q8VFK1; differential.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..314
FT /note="Olfactory receptor 1009"
FT /id="PRO_0000150859"
FT TOPO_DOM 1..25
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 26..46
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 47..54
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 76..99
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 121..133
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 155..196
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..217
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 218..237
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 238..258
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 259..271
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 293..314
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 5
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 97..189
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 314 AA; 35458 MW; EBD1D351B54FA50F CRC64;
MADENYTRIT EFIFIGLRYH PNLQVFLFLL FLLFYLVTMT GNLGMIILIR VDSRLHTPMY
FFLSHLSFVD ICFSSVVAPK MLTDFFADKK AISFLGCVLQ QWFFGFFVAI ECLLLASMAY
DRYVAICNPL LYSVAMSQRL CIQLVIGPYA VGFFNTMTHT TAAFRLPFCG SNIINHFFCD
MSPILSLICA DIRINKLLVF IVAGAVLIVS STTIIVSYFH ILIAILRIRS AEGRRKAFST
CSSHVTAVSI LYGTLFFIYV RPSAISSLDL NKVVSVFYTA VIPMLNPLIY SLRNKEVKSA
MGRTVAKAKV FLKN
