O1013_MOUSE
ID O1013_MOUSE Reviewed; 305 AA.
AC Q7TR96; Q8VG30;
DT 18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Olfactory receptor 1013 {ECO:0000312|EMBL:CAM26408.1};
DE AltName: Full=Olfactory receptor 213-2 {ECO:0000312|EMBL:AAL60996.1};
GN Name=Olfr1013 {ECO:0000312|EMBL:AAP71464.1, ECO:0000312|MGI:MGI:3030847};
GN Synonyms=Mor213-2 {ECO:0000312|EMBL:AAL60996.1};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1] {ECO:0000312|EMBL:AAL60996.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2] {ECO:0000312|EMBL:AAP71464.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=14611657; DOI=10.1186/gb-2003-4-11-r71;
RA Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A.,
RA Walker M., Williams E.M., Trask B.J.;
RT "Odorant receptor expressed sequence tags demonstrate olfactory expression
RT of over 400 genes, extensive alternate splicing and unequal expression
RT levels.";
RL Genome Biol. 4:R71.1-R71.13(2003).
RN [3] {ECO:0000312|EMBL:CAM26408.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [4] {ECO:0000312|EMBL:EDL27336.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Odorant receptor. {ECO:0000269|PubMed:11802173,
CC ECO:0000269|PubMed:14611657, ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY073333; AAL60996.1; -; Genomic_DNA.
DR EMBL; AY318208; AAP71464.1; -; Genomic_DNA.
DR EMBL; AL929285; CAM26408.1; -; Genomic_DNA.
DR EMBL; CH466519; EDL27336.1; -; Genomic_DNA.
DR CCDS; CCDS16218.1; -.
DR RefSeq; NP_666973.2; NM_146762.2.
DR AlphaFoldDB; Q7TR96; -.
DR SMR; Q7TR96; -.
DR STRING; 10090.ENSMUSP00000068173; -.
DR PaxDb; Q7TR96; -.
DR PRIDE; Q7TR96; -.
DR Ensembl; ENSMUST00000065626; ENSMUSP00000068173; ENSMUSG00000053287.
DR Ensembl; ENSMUST00000216397; ENSMUSP00000150201; ENSMUSG00000053287.
DR GeneID; 258757; -.
DR KEGG; mmu:258757; -.
DR UCSC; uc008kku.1; mouse.
DR CTD; 258757; -.
DR MGI; MGI:3030847; Olfr1013.
DR VEuPathDB; HostDB:ENSMUSG00000053287; -.
DR eggNOG; ENOG502T862; Eukaryota.
DR GeneTree; ENSGT00940000154333; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q7TR96; -.
DR OMA; FYSQAMS; -.
DR OrthoDB; 927196at2759; -.
DR PhylomeDB; Q7TR96; -.
DR TreeFam; TF352735; -.
DR BioGRID-ORCS; 258757; 0 hits in 66 CRISPR screens.
DR PRO; PR:Q7TR96; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q7TR96; protein.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Membrane;
KW Olfaction; Receptor; Reference proteome; Sensory transduction; Transducer;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..305
FT /note="Olfactory receptor 1013"
FT /id="PRO_0000393947"
FT TOPO_DOM 1..24
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 25..45
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 46..55
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 56..76
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 77..96
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 97..117
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 118..138
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 139..159
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 160..204
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 205..225
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 226..236
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..257
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 258..270
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 271..291
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 292..305
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DISULFID 96..178
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
FT CONFLICT 145
FT /note="V -> A (in Ref. 1; AAL60996)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 305 AA; 34324 MW; AEE7430EFF8AA3C4 CRC64;
MDQNNNTVSE FIMLGFTTDP VIQKVLFAVF LVVYTLTLMG NSSLIMLICN DSRLHTPMYF
FIGNLSFLDL GLSSVYTPKI LETCISEDKS ISFAGCVAQF FFSAALDYTE CYLLAAMAYD
RYVAISKPLL YSQAMSLKLC VCFVVASYVG GFINSVIITK DTFALTFCND NVIDDFFCDI
PPLVKLACGK KKSFQSVLFF LLTSNVIIPI VFILATYLFI IATILRIRST QGRLKAFSTC
SSHLISVTLY YGSILYIYAR PRSSYSLDRD KIVSTFYTVV FPMLNPLIYS LRNKDVKEAL
NKLLK
