O1020_MOUSE
ID O1020_MOUSE Reviewed; 317 AA.
AC Q8VFK7;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=Olfactory receptor 1020;
DE AltName: Full=Olfactory receptor 201-2;
GN Name=Olfr1020; Synonyms=Mor201-2;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY073517; AAL61180.1; -; Genomic_DNA.
DR EMBL; AY318215; AAP71470.1; -; Genomic_DNA.
DR CCDS; CCDS16224.1; -.
DR RefSeq; NP_666791.1; NM_146580.2.
DR AlphaFoldDB; Q8VFK7; -.
DR SMR; Q8VFK7; -.
DR STRING; 10090.ENSMUSP00000058242; -.
DR GlyGen; Q8VFK7; 1 site.
DR iPTMnet; Q8VFK7; -.
DR PhosphoSitePlus; Q8VFK7; -.
DR PaxDb; Q8VFK7; -.
DR PRIDE; Q8VFK7; -.
DR Antibodypedia; 58995; 55 antibodies from 16 providers.
DR Ensembl; ENSMUST00000055840; ENSMUSP00000058242; ENSMUSG00000046975.
DR Ensembl; ENSMUST00000215347; ENSMUSP00000150285; ENSMUSG00000046975.
DR GeneID; 258573; -.
DR KEGG; mmu:258573; -.
DR UCSC; uc008kla.2; mouse.
DR CTD; 258573; -.
DR MGI; MGI:3030854; Olfr1020.
DR VEuPathDB; HostDB:ENSMUSG00000046975; -.
DR eggNOG; ENOG502RF13; Eukaryota.
DR GeneTree; ENSGT01050000244954; -.
DR HOGENOM; CLU_012526_0_1_1; -.
DR InParanoid; Q8VFK7; -.
DR OMA; VRGRNQT; -.
DR OrthoDB; 1171129at2759; -.
DR PhylomeDB; Q8VFK7; -.
DR TreeFam; TF352753; -.
DR BioGRID-ORCS; 258573; 1 hit in 65 CRISPR screens.
DR PRO; PR:Q8VFK7; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q8VFK7; protein.
DR ExpressionAtlas; Q8VFK7; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..317
FT /note="Olfactory receptor 1020"
FT /id="PRO_0000150861"
FT TOPO_DOM 1..32
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 33..53
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 54..61
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 83..106
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 128..140
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 141..161
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 162..203
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 225..244
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 245..265
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 266..278
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 300..317
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 12
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 104..196
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 317 AA; 35284 MW; DF2360B3FDB8C373 CRC64;
MVRSGKGIQN KNATEVTEFI LLGLSDNPDL QGVLFALFLI IYTMTLVGNL GMMALIKIDR
SLHTPMYFFL SSLSFVDASY SSSVTPKMLV NLMAEDKSIS FNGCATQFFF FGSFLGTECF
LLAMMAYDRY AAIWNPLLYP VLMSGRICFM LVSTSFLAGF GNAAIHTGMT FRLSFCGSNK
INHFYCDTPP LLKLSCSDTH INGIVIMAFS SFNVISCVLI VLISYLCILI AILKMPSAEG
RHKAFSTCAS HLMAVTIFFG TILFMYLRPT SSYSMEQDKV VSVFYTVVIP MLNPLIYSLK
NKDVKKAVKK ILHNYVV
