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O1030_MOUSE
ID   O1030_MOUSE             Reviewed;         318 AA.
AC   Q8VFL5;
DT   10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 136.
DE   RecName: Full=Olfactory receptor 1030;
DE   AltName: Full=Olfactory receptor 196-2;
GN   Name=Olfr1030; Synonyms=Mor196-2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11802173; DOI=10.1038/nn800;
RA   Zhang X., Firestein S.;
RT   "The olfactory receptor gene superfamily of the mouse.";
RL   Nat. Neurosci. 5:124-133(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA   Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA   Trask B.J.;
RT   "Different evolutionary processes shaped the mouse and human olfactory
RT   receptor gene families.";
RL   Hum. Mol. Genet. 11:535-546(2002).
RN   [3]
RP   ERRATUM OF PUBMED:11875048.
RA   Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA   Trask B.J.;
RL   Hum. Mol. Genet. 11:1683-1683(2002).
CC   -!- FUNCTION: Potential odorant receptor.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAP71477.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AY073509; AAL61172.1; -; Genomic_DNA.
DR   EMBL; AY318225; AAP71477.1; ALT_INIT; Genomic_DNA.
DR   CCDS; CCDS16231.1; -.
DR   RefSeq; NP_666799.1; NM_146588.2.
DR   AlphaFoldDB; Q8VFL5; -.
DR   SMR; Q8VFL5; -.
DR   STRING; 10090.ENSMUSP00000053309; -.
DR   GlyGen; Q8VFL5; 1 site.
DR   PaxDb; Q8VFL5; -.
DR   PRIDE; Q8VFL5; -.
DR   Ensembl; ENSMUST00000056849; ENSMUSP00000053309; ENSMUSG00000044923.
DR   GeneID; 258581; -.
DR   KEGG; mmu:258581; -.
DR   UCSC; uc008klh.2; mouse.
DR   CTD; 258581; -.
DR   MGI; MGI:3030864; Olfr1030.
DR   VEuPathDB; HostDB:ENSMUSG00000044923; -.
DR   eggNOG; ENOG502TC7V; Eukaryota.
DR   GeneTree; ENSGT01050000244907; -.
DR   HOGENOM; CLU_012526_1_0_1; -.
DR   InParanoid; Q8VFL5; -.
DR   OMA; AGPYVYG; -.
DR   OrthoDB; 941671at2759; -.
DR   PhylomeDB; Q8VFL5; -.
DR   TreeFam; TF352751; -.
DR   BioGRID-ORCS; 258581; 2 hits in 65 CRISPR screens.
DR   PRO; PR:Q8VFL5; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; Q8VFL5; protein.
DR   ExpressionAtlas; Q8VFL5; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR   GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR   GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..318
FT                   /note="Olfactory receptor 1030"
FT                   /id="PRO_0000150862"
FT   TOPO_DOM        1..31
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        53..60
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        82..105
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        127..139
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        161..202
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        203..223
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        224..243
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        265..277
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        278..298
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        299..318
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        11
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        103..195
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   318 AA;  36382 MW;  7DFFF1B58DBCAB43 CRC64;
     MLAPKKMVRG NYSMVTEFIL LGLTDRPELQ PLLFVLFLVI YLITVGGNLG MMVLIRIDSR
     LHTPMYYFLA SLSCLDLCYS TNVTPKMLVN FLSEKKTISY AACLVQCYFF IAMVITEYYM
     LAVMAYDRYM AICNPLLYSS KMSKGVCVRL IAGPYIYGFL SGLMETMWTY RLTFCGSNII
     NHFYCADPPL IRLSCSDTFI KETSMFVVAG FNLSNSLFII LISYLFILIA ILRMRSAEGR
     RKAFSTCGSH LVAVTVFYGT LFCMYVRPPT DKSVEQSKII AVFYTFVSPM LNPIIYSLRN
     KDVKHAFWKL VRRNVLSK
 
 
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