ID   O1078_RAT               Reviewed;         333 AA.
AC   P23265;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Olfactory receptor 1078;
DE   AltName: Full=Olfactory receptor-like protein F3;
GN   Name=Olr1078;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1840504; DOI=10.1016/0092-8674(91)90418-x;
RA   Buck L., Axel R.;
RT   "A novel multigene family may encode odorant receptors: a molecular basis
RT   for odor recognition.";
RL   Cell 65:175-187(1991).
CC   -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Olfactory epithelium.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; M64376; AAA41739.1; -; mRNA.
DR   PIR; A23701; A23701.
DR   RefSeq; NP_997480.1; NM_207597.1.
DR   AlphaFoldDB; P23265; -.
DR   SMR; P23265; -.
DR   GlyGen; P23265; 1 site.
DR   GeneID; 299593; -.
DR   KEGG; rno:299593; -.
DR   UCSC; RGD:1333657; rat.
DR   CTD; 299593; -.
DR   RGD; 1333657; Olr1078.
DR   InParanoid; P23265; -.
DR   OrthoDB; 984499at2759; -.
DR   PhylomeDB; P23265; -.
DR   PRO; PR:P23265; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..333
FT                   /note="Olfactory receptor 1078"
FT                   /id="PRO_0000150872"
FT   TOPO_DOM        1..25
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        26..50
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        51..57
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..79
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..100
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..120
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        121..139
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..158
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        159..196
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..219
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        220..236
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        237..260
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        261..272
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..292
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        293..333
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        5
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        97..189
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   333 AA;  37541 MW;  918AD817099ECCA3 CRC64;
     MDSSNRTRVS EFLLLGFVEN KDLQPLIYGL FLSMYLVTVI GNISIIVAII SDPCLHTPMY
     FFLSNLSFVD ICFISTTVPK MLVNIQTQNN VITYAGCITQ IYFFLLFVEL DNFLLTIMAY
     DRYVAICHPM HYTVIMNYKL CGFLVLVSWI VSVLHALFQS LMMLALPFCT HLEIPHYFCE
     PNQVIQLTCS DAFLNDLVIY FTLVLLATVP LAGIFYSYFK IVSSICAISS VHGKYKAFST
     CASHLSVVSL FYCTGLGVYL SSAANNSSQA SATASVMYTV VTPMVNPFIY SLRNKDVKSV
     LKKTLCEEVI RSPPSLLHFF LVLCHLPCFI FCY