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O1094_MOUSE
ID   O1094_MOUSE             Reviewed;         330 AA.
AC   Q8VF13;
DT   10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Olfactory receptor 1094;
DE   AltName: Full=Olfactory receptor 179-7;
GN   Name=Olfr1094; Synonyms=Mor179-7;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11802173; DOI=10.1038/nn800;
RA   Zhang X., Firestein S.;
RT   "The olfactory receptor gene superfamily of the mouse.";
RL   Nat. Neurosci. 5:124-133(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA   Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA   Trask B.J.;
RT   "Different evolutionary processes shaped the mouse and human olfactory
RT   receptor gene families.";
RL   Hum. Mol. Genet. 11:535-546(2002).
RN   [3]
RP   ERRATUM OF PUBMED:11875048.
RA   Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA   Trask B.J.;
RL   Hum. Mol. Genet. 11:1683-1683(2002).
CC   -!- FUNCTION: Potential odorant receptor.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; AY073728; AAL61391.1; -; Genomic_DNA.
DR   EMBL; AY318291; AAP71520.1; -; Genomic_DNA.
DR   CCDS; CCDS16269.1; -.
DR   RefSeq; NP_666477.1; NM_146365.2.
DR   AlphaFoldDB; Q8VF13; -.
DR   SMR; Q8VF13; -.
DR   STRING; 10090.ENSMUSP00000100846; -.
DR   GlyGen; Q8VF13; 1 site.
DR   PhosphoSitePlus; Q8VF13; -.
DR   PaxDb; Q8VF13; -.
DR   PRIDE; Q8VF13; -.
DR   DNASU; 258362; -.
DR   Ensembl; ENSMUST00000105211; ENSMUSP00000100846; ENSMUSG00000044213.
DR   Ensembl; ENSMUST00000217509; ENSMUSP00000148902; ENSMUSG00000044213.
DR   GeneID; 258362; -.
DR   KEGG; mmu:258362; -.
DR   UCSC; uc008kmz.2; mouse.
DR   CTD; 258362; -.
DR   MGI; MGI:3030928; Olfr1094.
DR   VEuPathDB; HostDB:ENSMUSG00000044213; -.
DR   eggNOG; ENOG502SHA3; Eukaryota.
DR   GeneTree; ENSGT00940000153301; -.
DR   HOGENOM; CLU_012526_1_0_1; -.
DR   InParanoid; Q8VF13; -.
DR   OMA; TNMPNNT; -.
DR   OrthoDB; 960379at2759; -.
DR   PhylomeDB; Q8VF13; -.
DR   TreeFam; TF352753; -.
DR   BioGRID-ORCS; 258362; 3 hits in 66 CRISPR screens.
DR   PRO; PR:Q8VF13; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; Q8VF13; protein.
DR   ExpressionAtlas; Q8VF13; differential.
DR   GO; GO:0030425; C:dendrite; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0045202; C:synapse; IEA:GOC.
DR   GO; GO:0004993; F:G protein-coupled serotonin receptor activity; IBA:GO_Central.
DR   GO; GO:0030594; F:neurotransmitter receptor activity; IBA:GO_Central.
DR   GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR   GO; GO:0007268; P:chemical synaptic transmission; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR   GO; GO:0007187; P:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; IBA:GO_Central.
DR   GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   InterPro; IPR036905; OR_1094.
DR   PANTHER; PTHR24247:SF126; PTHR24247:SF126; 1.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..330
FT                   /note="Olfactory receptor 1094"
FT                   /id="PRO_0000150867"
FT   TOPO_DOM        1..37
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        59..66
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        88..111
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        133..145
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        167..208
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..229
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        230..249
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        250..270
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        271..283
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        305..330
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        17
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        109..201
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   330 AA;  37363 MW;  64916C0E6013E87C CRC64;
     MSIHSPGYTV RRIPVNNVTD TTMFILTGFT DDADLQVLLF LLFFVIYLFT LIGNLGLVLL
     VIGDSRLHNP MYYFLSVLSF LDACYSTVVT PKMLVNFISN DKSISYPGCV TEMFLFVTFG
     TTECFLLAAM AYDRFVAIYN PLLYAVKMSP RVYIPLIIAC YSGGIMHATI HTVATFSLSF
     CASNEIRHVF CDIPPLLAIS CSNTNINQLL LFYCVGSIEI ITILIVLVSY SFILFAILKM
     NSAEGRRKIF STCGSHLTGV SIYHGTILFM YVRPSSNYAL EHDMIVSTFY TIVIPMLNPI
     IYSLRNKDVK EAMKKIFERN FFMNKVHFKL
 
 
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