O1094_MOUSE
ID O1094_MOUSE Reviewed; 330 AA.
AC Q8VF13;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Olfactory receptor 1094;
DE AltName: Full=Olfactory receptor 179-7;
GN Name=Olfr1094; Synonyms=Mor179-7;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY073728; AAL61391.1; -; Genomic_DNA.
DR EMBL; AY318291; AAP71520.1; -; Genomic_DNA.
DR CCDS; CCDS16269.1; -.
DR RefSeq; NP_666477.1; NM_146365.2.
DR AlphaFoldDB; Q8VF13; -.
DR SMR; Q8VF13; -.
DR STRING; 10090.ENSMUSP00000100846; -.
DR GlyGen; Q8VF13; 1 site.
DR PhosphoSitePlus; Q8VF13; -.
DR PaxDb; Q8VF13; -.
DR PRIDE; Q8VF13; -.
DR DNASU; 258362; -.
DR Ensembl; ENSMUST00000105211; ENSMUSP00000100846; ENSMUSG00000044213.
DR Ensembl; ENSMUST00000217509; ENSMUSP00000148902; ENSMUSG00000044213.
DR GeneID; 258362; -.
DR KEGG; mmu:258362; -.
DR UCSC; uc008kmz.2; mouse.
DR CTD; 258362; -.
DR MGI; MGI:3030928; Olfr1094.
DR VEuPathDB; HostDB:ENSMUSG00000044213; -.
DR eggNOG; ENOG502SHA3; Eukaryota.
DR GeneTree; ENSGT00940000153301; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q8VF13; -.
DR OMA; TNMPNNT; -.
DR OrthoDB; 960379at2759; -.
DR PhylomeDB; Q8VF13; -.
DR TreeFam; TF352753; -.
DR BioGRID-ORCS; 258362; 3 hits in 66 CRISPR screens.
DR PRO; PR:Q8VF13; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q8VF13; protein.
DR ExpressionAtlas; Q8VF13; differential.
DR GO; GO:0030425; C:dendrite; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0004993; F:G protein-coupled serotonin receptor activity; IBA:GO_Central.
DR GO; GO:0030594; F:neurotransmitter receptor activity; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007268; P:chemical synaptic transmission; IBA:GO_Central.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007187; P:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; IBA:GO_Central.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR InterPro; IPR036905; OR_1094.
DR PANTHER; PTHR24247:SF126; PTHR24247:SF126; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..330
FT /note="Olfactory receptor 1094"
FT /id="PRO_0000150867"
FT TOPO_DOM 1..37
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..58
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 59..66
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 88..111
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 112..132
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 133..145
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 167..208
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 230..249
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 250..270
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 271..283
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 305..330
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 17
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 109..201
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 330 AA; 37363 MW; 64916C0E6013E87C CRC64;
MSIHSPGYTV RRIPVNNVTD TTMFILTGFT DDADLQVLLF LLFFVIYLFT LIGNLGLVLL
VIGDSRLHNP MYYFLSVLSF LDACYSTVVT PKMLVNFISN DKSISYPGCV TEMFLFVTFG
TTECFLLAAM AYDRFVAIYN PLLYAVKMSP RVYIPLIIAC YSGGIMHATI HTVATFSLSF
CASNEIRHVF CDIPPLLAIS CSNTNINQLL LFYCVGSIEI ITILIVLVSY SFILFAILKM
NSAEGRRKIF STCGSHLTGV SIYHGTILFM YVRPSSNYAL EHDMIVSTFY TIVIPMLNPI
IYSLRNKDVK EAMKKIFERN FFMNKVHFKL
