O1102_MOUSE
ID O1102_MOUSE Reviewed; 324 AA.
AC Q8VES2; A2AVB4;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 3.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Olfactory receptor 1102;
DE AltName: Full=Olfactory receptor 179-4;
GN Name=Olfr1102; Synonyms=Mor179-4;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [2]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 57-324.
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY318299; AAP71527.1; -; Genomic_DNA.
DR EMBL; AL929417; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AY073828; AAL61491.1; -; Genomic_DNA.
DR CCDS; CCDS16275.1; -.
DR RefSeq; NP_997037.2; NM_207154.2.
DR AlphaFoldDB; Q8VES2; -.
DR SMR; Q8VES2; -.
DR STRING; 10090.ENSMUSP00000052861; -.
DR GlyGen; Q8VES2; 3 sites.
DR PhosphoSitePlus; Q8VES2; -.
DR PaxDb; Q8VES2; -.
DR PRIDE; Q8VES2; -.
DR DNASU; 228228; -.
DR Ensembl; ENSMUST00000055129; ENSMUSP00000052861; ENSMUSG00000049843.
DR Ensembl; ENSMUST00000214002; ENSMUSP00000149634; ENSMUSG00000049843.
DR GeneID; 228228; -.
DR KEGG; mmu:228228; -.
DR UCSC; uc008kng.2; mouse.
DR CTD; 228228; -.
DR MGI; MGI:3030936; Olfr1102.
DR VEuPathDB; HostDB:ENSMUSG00000049843; -.
DR eggNOG; ENOG502SHA3; Eukaryota.
DR GeneTree; ENSGT00940000153301; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q8VES2; -.
DR OMA; DTHINRC; -.
DR OrthoDB; 960379at2759; -.
DR PhylomeDB; Q8VES2; -.
DR TreeFam; TF352753; -.
DR BioGRID-ORCS; 228228; 2 hits in 65 CRISPR screens.
DR PRO; PR:Q8VES2; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q8VES2; protein.
DR GO; GO:0030425; C:dendrite; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0004993; F:G protein-coupled serotonin receptor activity; IBA:GO_Central.
DR GO; GO:0030594; F:neurotransmitter receptor activity; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007268; P:chemical synaptic transmission; IBA:GO_Central.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007187; P:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; IBA:GO_Central.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..324
FT /note="Olfactory receptor 1102"
FT /id="PRO_0000150868"
FT TOPO_DOM 1..37
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..58
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 59..66
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 88..111
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 112..132
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 133..145
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 167..208
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 230..249
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 250..270
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 271..283
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 305..324
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 17
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 101
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 277
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 109..201
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
FT CONFLICT 95
FT /note="V -> A (in Ref. 4; AAL61491)"
FT /evidence="ECO:0000305"
FT CONFLICT 219
FT /note="E -> K (in Ref. 1; AAP71527 and 4; AAL61491)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 324 AA; 36292 MW; C2EA0B88952F4606 CRC64;
MPRTPSYTNT KTTQVNNVTE ITVFILLGFT DDVDMNIFLF ILFLAIYVVT LIGNLGLVVL
VIEDSRLHNP MYYFLTVLSS LDACFSSVLT PKMLVNFLSK NKSISFAGCA TQMLLFVTFG
TTECFLLAAM AYDRYLAIYS PLLYAVRMSP RVYVPLIIAS YTGGILHATI HTVATFSLSF
CGSNEIRHVF CDIPPLLALS CSDTHLNQLL LFYCAGSIEL ITILIVLVSY GFVLLAILKI
NSAEGRRKIF STCGAHLTGV SIFHGTILFM YVRPSSNYTL EQDMVVSTFY TIVIPMLNPI
IYSLRNKDVK EAMRKLLKRK LVHE
