ID   ARPR_PSEPU              Reviewed;         210 AA.
AC   Q9KJC4;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Probable HTH-type transcriptional regulator ArpR;
DE   AltName: Full=Antibiotic efflux pump ArpABC operon regulator;
GN   Name=arpR;
OS   Pseudomonas putida (Arthrobacter siderocapsulatus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=303;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 700801 / S12;
RX   PubMed=11160799; DOI=10.1099/00221287-147-1-43;
RA   Kieboom J., de Bont J.A.M.;
RT   "Identification and molecular characterization of an efflux system involved
RT   in Pseudomonas putida S12 multidrug resistance.";
RL   Microbiology 147:43-51(2001).
CC   -!- FUNCTION: Probable regulatory protein for the antibiotic efflux pump
CC       arpABC operon. May function as a repressor (By similarity).
CC       {ECO:0000250}.
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DR   EMBL; AF183959; AAF73830.1; -; Genomic_DNA.
DR   RefSeq; WP_010952495.1; NZ_PZKR01000020.1.
DR   AlphaFoldDB; Q9KJC4; -.
DR   SMR; Q9KJC4; -.
DR   STRING; 1240350.AMZE01000001_gene2852; -.
DR   PATRIC; fig|303.175.peg.5272; -.
DR   eggNOG; COG1309; Bacteria.
DR   OMA; MMEIIFH; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   InterPro; IPR013572; Tscrpt_reg_MAATS_C.
DR   Pfam; PF08361; TetR_C_2; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF48498; SSF48498; 1.
DR   PROSITE; PS01081; HTH_TETR_1; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..210
FT                   /note="Probable HTH-type transcriptional regulator ArpR"
FT                   /id="PRO_0000070624"
FT   DOMAIN          10..70
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT   DNA_BIND        33..52
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   210 AA;  23797 MW;  A167F57269CC2F91 CRC64;
     MVRRTKEEAQ ETRAQIIEAA ERAFYKRGVA RTTLADIAEL AGVTRGAIYW HFNNKAELVQ
     ALLDSLHETH DHLARASESE DELDPLGCMR KLLLQVFNEL VLDARTRRIN EILHHKCEFT
     DDMCEIRQQR QSAVLDCHKG ITLALANAVR RGQLPGELDV ERAAVAMFAY VDGLIGRWLL
     LPDSVDLLGD VEKWVDTGLD MLRLSPALRK