ID   O1493_RAT               Reviewed;         312 AA.
AC   P23271;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Olfactory receptor 1493;
DE   AltName: Full=Olfactory receptor-like protein I8;
GN   Name=Olr1493;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1840504; DOI=10.1016/0092-8674(91)90418-x;
RA   Buck L., Axel R.;
RT   "A novel multigene family may encode odorant receptors: a molecular basis
RT   for odor recognition.";
RL   Cell 65:175-187(1991).
CC   -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Olfactory epithelium.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; M64387; AAA41750.1; -; mRNA.
DR   PIR; G23701; G23701.
DR   RefSeq; NP_001006610.1; NM_001006609.1.
DR   AlphaFoldDB; P23271; -.
DR   SMR; P23271; -.
DR   GlyGen; P23271; 1 site.
DR   GeneID; 363640; -.
DR   KEGG; rno:363640; -.
DR   CTD; 363640; -.
DR   RGD; 1549701; Olr1493.
DR   InParanoid; P23271; -.
DR   OrthoDB; 924696at2759; -.
DR   PhylomeDB; P23271; -.
DR   PRO; PR:P23271; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..312
FT                   /note="Olfactory receptor 1493"
FT                   /id="PRO_0000150877"
FT   TOPO_DOM        1..23
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        24..48
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        49..55
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..77
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        78..98
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..118
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        119..137
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..156
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        157..194
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        195..217
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        218..234
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..258
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        259..270
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..290
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        291..312
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        95..187
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   312 AA;  35316 MW;  D84D101F2DB6C29A CRC64;
     MNNKTVITHF LLLGLPIPPE HQQLFFALFL IMYLTTFLGN LLIVVLVQLD SHLHTPMYLF
     LSNLSFSDLC FSSVTMLKLL QNIQSQVPSI SYAGCLTQIF FFLLFGYLGN FLLVAMAYDR
     YVAICFPLHY TNIMSHKLCT CLLLVFWIMT SSHAMMHTLL AARLSFCENN VLLNFFCDLF
     VLLKLACSDT YVNELMIHIM GVIIIVIPFV LIVISYAKII SSILKVPSTQ SIHKVFSTCG
     SHLSVVSLFY GTIIGLYLCP SGDNFSLKGS AMAMMYTVVT PMLNPFIYSL RNRDMKQALI
     RVTCSKKISL PW